Filtered By:
Source: Biochemical and Biophysical Research communications
Nutrition: Turmeric
This page shows you your search results in order of date.
Order by Relevance | Date
Total 2 results found since Jan 2013.
Combination of azacytidine and curcumin is a potential alternative in decitabine-resistant colorectal cancer cells with attenuated deoxycytidine kinase
Biochem Biophys Res Commun. 2021 Sep 22;578:157-162. doi: 10.1016/j.bbrc.2021.09.041. Online ahead of print.ABSTRACTDecitabine (DAC), a DNA methyltransferase (DNMT) inhibitor is a novel anti-cancer drug regulating epigenetic mechanisms. Similar to conventional anti-cancer drugs, drug resistance to DAC also has been reported, resulting in tumor recurrence. Our previous study using colorectal cancer HCT116 cells found the decrease in deoxycytidine kinase (dCK) (activation enzyme of DAC) and the increase in cytidine deaminase (inactivation enzyme of DAC) in acquired DAC-resistant HCT116 (HCT116/DAC) cells. The aim of our stud...
Source: Biochemical and Biophysical Research communications - September 27, 2021 Category: Biochemistry Authors: Mika Hosokawa Risako Seiki Seigo Iwakawa Ken-Ichi Ogawara Source Type: research
