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TGF- β1 acts as mediator in fluoride-induced autophagy in the mouse osteoblast cells.
TGF-β1 acts as mediator in fluoride-induced autophagy in the mouse osteoblast cells. Food Chem Toxicol. 2018 Mar 02;: Authors: Zhao Y, Li Y, Gao Y, Yuan M, Manthari RK, Wang J, Wang J Abstract It is well known that excess fluoride intake can result in fluorosis, which is a serious public health problem. TGF-β1 affects a wide variety of cellular activities and plays an important role in fluorosis. Recent literature proved that fluoride induces autophagy, however, the mechanism is still unclear, and the role of TGF-β1 in the fluoride-induced autophagy should be further illustrated. Therefore, in this...
Source: Food and Chemical Toxicology - March 2, 2018 Category: Food Science Authors: Zhao Y, Li Y, Gao Y, Yuan M, Manthari RK, Wang J, Wang J Tags: Food Chem Toxicol Source Type: research