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Source: Experimental Eye Research
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Total 2 results found since Jan 2013.

siRNA high throughput screening identifies regulators of chloropicrin and hydrogen fluoride injury in human corneal epithelial cell models
Exp Eye Res. 2022 Jul 9:109169. doi: 10.1016/j.exer.2022.109169. Online ahead of print.ABSTRACTCorneal injuries induced by various toxicants result in similar clinical presentations such as corneal opacity and neovascularization. Many studies suggest that several weeks post-exposure a convergence of the molecular mechanisms drives these progressive pathologies. However, chemical agents vary in toxicological properties, and early molecular responses are anticipated to be somewhat dissimilar for different toxicants. We chose 3120 targets from the Dharmacon Human Druggable genome to screen for chloropicrin (CP) and hydrogen f...
Source: Experimental Eye Research - July 12, 2022 Category: Opthalmology Authors: Albert L Ruff Robert D Causey Jeffrey A Koenig Cristina V LaGrasta Amber M Gomez Bailey T Chalmers John G Lehman Source Type: research