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GM ‐CSF ameliorates microvascular barrier integrity via pericyte‐derived Ang‐1 in wound healing
Abstract Skin wound healing involves complex coordinated interactions of cells, tissues, and mediators. Maintaining microvascular barrier integrity is one of the key events for endothelial homeostasis during wound healing. Vasodilation is observed after vasoconstriction, which causes blood vessels to become porous, facilitates leukocyte infiltration and aids angiogenesis at the wound‐area, postinjury. Eventually, vessel integrity has to be reestablished for vascular maturation. Numerous studies have found that granulocyte macrophage colony‐stimulating factor (GM‐CSF) accelerates wound healing by inducing recruitment ...
Source: Wound Repair and Regeneration - February 16, 2018 Category: Surgery Authors: Min Yan, Yange Hu, Min Yao, Shisan Bao, Yong Fang Tags: Original Research ‐Basic Science Source Type: research

GM ‐CSF ameliorates microvascular barrier integrity via pericytes‐derived Ang‐1 in wound healing
Abstract Skin wound healing involves complex coordinated interactions of cells, tissues, and mediators. Maintaining microvascular barrier integrity is one of the key events for endothelial homeostasis during wound healing. Vasodilation is observed after vasoconstriction, which causes blood vessels to become porous, facilitates leukocyte infiltration and aids angiogenesis at the wound‐area, postinjury. Eventually, vessel integrity has to be reestablished for vascular maturation. Numerous studies have found that granulocyte macrophage colony‐stimulating factor (GM‐CSF) accelerates wound healing by inducing recruitment ...
Source: Wound Repair and Regeneration - February 16, 2018 Category: Surgery Authors: Min Yan, Yange Hu, Min Yao, Shisan Bao, Yong Fang Tags: Original Research ‐Basic Science Source Type: research

GM ‐CSF Ameliorates Micro‐vascular Barrier Integrity via Pericytes Derived Ang‐1 in Wound Healing
Conclusions: Our data indicate that GM‐CSF ameliorates micro‐vascular barrier integrity via pericyte derived Ang‐1 during wound healing. This article is protected by copyright. All rights reserved.
Source: Wound Repair and Regeneration - January 12, 2018 Category: Surgery Authors: Min Yan, Yange Hu, Min Yao, Shisan Bao, Yong Fang Tags: Original Research ‐Basic Science Source Type: research