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Design and delivery of therapeutic siRNAs: application to MERS-Coronavirus.
CONCLUSION: The efficacy of siRNA-based therapeutics has been used not only against many viral diseases but also against non-viral diseases, cancer, dominant genetic disorders, and autoimmune disease. This innovative technology has attracted researchers, academia and pharmaceuticals industries towards designing and development of highly effective and targeted disease therapy. By using this technology, an effective and potential siRNAs can be designed, delivered and their efficacy with toxic effects and immunogenic responses can be tested against MERS-CoV. PMID: 29119921 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Design - November 8, 2017 Category: Drugs & Pharmacology Authors: Sohrab SS, El-Kafrawy SA, Mirza Z, Kamal MA, Azhar EI Tags: Curr Pharm Des Source Type: research