Filtered By:
Source: Archives of Virology
Infectious Disease: Chikungunya
This page shows you your search results in order of date.
Order by Relevance | Date
Total 1 results found since Jan 2013.
Regulation of the chikungunya-virus-induced innate inflammatory response by protein tyrosine phosphatase non-receptor 6 in muscle cells
AbstractChikungunya virus (CHIKV)-induced myositis is an emerging affliction with high incidence globally. Given the essential regulatory role of protein tyrosine phosphatase non-receptor 6 (PTPN6) in virus-induced myositis, the expression of the PTPN6 and TNF- α genes in a CHIKV-infected muscle cell line was examined by quantitative PCR, and the expression of PTPN6 and STAT 3 was examined by immunoblotting. In addition, the effect of PTPN6 siRNA treatment on TNF-α gene expression was assessed. Increased higher expression of PTPN6 and TNF-α, and signifi cant upregulation of TNF-α upon PTPN6 siRNA treatment were observe...
Source: Archives of Virology - January 1, 2018 Category: Virology Source Type: research
