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Source: Molecular and Cellular Endocrinology
Condition: Cholesterol

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SNAREs and cholesterol movement for steroidogenesis
Publication date: 5 February 2017 Source:Molecular and Cellular Endocrinology, Volume 441 Author(s): Fredric B. Kraemer, Wen-Jun Shen, Salman Azhar Steroidogenesis is a complex process through which cholesterol traffics to mitochondria and is converted via a series of enzymatic steps to steroid hormones. Although the rate-limiting step in this process is the movement of cholesterol from the outer to the inner mitochondrial membrane via the actions of StAR, a continuous supply of cholesterol must be delivered to the outer mitochondrial membrane during active steroidogenesis and this is derived from multiple sources, includ...
Source: Molecular and Cellular Endocrinology - January 8, 2017 Category: Endocrinology Source Type: research