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Source: Molecular Immunology
Nutrition: Antidoxidants
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Carbon monoxide releasing molecule-2 protects against particulate matter-induced lung inflammation by inhibiting TLR2 and 4/ROS/NLRP3 inflammasome activation
Publication date: August 2019Source: Molecular Immunology, Volume 112Author(s): Chiang-Wen Lee, Miao-Ching Chi, Lee-Fen Hsu, Chuen-Mao Yang, Tsui-Hua Hsu, Chu-Chun Chuang, Wei-Ning Lin, Pei-Ming Chu, I-Ta LeeAbstractExposure to airborne particulate matter (PM) not only causes lung inflammation and chronic respiratory diseases, but also increases the incidence and mortality of cardiopulmonary diseases. The nucleotide-binding domain and leucine-rich repeat protein 3 (NLRP3) inflammasome activation has been shown to play a critical role in the formation of many chronic disorders. On the other hand, carbon monoxide (CO) has be...
Source: Molecular Immunology - May 30, 2019 Category: Allergy & Immunology Source Type: research
