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Source: Cell Reports
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Splicing and Chromatin Factors Jointly Regulate Epidermal Differentiation
Publication date: 30 October 2018Source: Cell Reports, Volume 25, Issue 5Author(s): Sabine E.J. Tanis, Pascal W.T.C. Jansen, Huiqing Zhou, Simon J. van Heeringen, Michiel Vermeulen, Markus Kretz, Klaas W. MulderSummaryEpidermal homeostasis requires balanced progenitor cell proliferation and loss of differentiated cells from the epidermal surface. During this process, cells undergo major changes in their transcriptional programs to accommodate new cellular functions. We found that transcriptional and post-transcriptional mechanisms underlying these changes jointly control genes involved in cell adhesion, a key process in e...
Source: Cell Reports - November 1, 2018 Category: Cytology Source Type: research
