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Source: Clinical Cancer Research
Therapy: Immunotherapy
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Total 1 results found since Jan 2013.
Chemerin reactivates PTEN and suppresses PD-L1 in tumor cells via modulation of a novel CMKLR1-mediated signaling cascade.
CONCLUSIONS: Collectively, our data show a novel link between chemerin, PTEN and PD-L1 in human tumor cells, that may have a role in improving T cell-mediated immunotherapies.
PMID: 32605911 [PubMed - as supplied by publisher]
Source: Clinical Cancer Research - June 29, 2020 Category: Cancer & Oncology Authors: Rennier KR, Shin WJ, Krug E, Virdi GS, Pachynski RK Tags: Clin Cancer Res Source Type: research
