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Source: Autophagy
Infectious Disease: Hepatitis B
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Total 6 results found since Jan 2013.
CCDC88A/GIV promotes HBV replication and progeny secretion via enhancing endosomal trafficking and blocking autophagic degradation
In conclusion, CCDC88A/GIV enhanced HBV replication by increasing endosomal trafficking and reducing autophagic degradation of HBV antigens, suggesting that CCDC88A/GIV-mediated endosomal trafficking plays an important role in HBV replication and progeny secretion.AbbreviationsACTB: actin beta; AO: acridine orange; ATF6: activating transcription factor 6; CCDC88A/GIV: coiled-coil domain containing 88A; CLTC: clathrin heavy chain; CQ: chloroquine; DAPI: 4',6-diamidino-2-phenylindole; DNM2: dynamin 2; ER: endoplasmic reticulum; ERN1: endoplasmic reticulum to nucleus signaling 1; EIF2A: eukaryotic translation initiation facto...
Source: Autophagy - June 30, 2021 Category: Cytology Authors: Xueyu Wang Zhiqiang Wei Tingyu Lan Yulin He Bin Cheng Ruimin Li Hongxia Chen Fahong Li Guohua Liu Bin Jiang Yong Lin Mengji Lu Zhongji Meng Source Type: research
