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Source: Oncology Research
Drug: Methotrexate

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Total 1 results found since Jan 2013.

CLIC1 induces drug resistance in human choriocarcinoma through positive regulation of MRP1.
In conclusion, our results suggest that CLIC1 may serve as a critical mediator of chemoresistance in human choriocarcinoma JeG3 cells. The CLIC1-mediated chemoresistance is achieved through positive regulation of MRP1. Depletion of either CLIC1 or its downstream MRP1 may be a promising therapeutic strategy concerning reversing the chemo-resistance in human choriocarcinoma JeG3 cells. PMID: 27983917 [PubMed - as supplied by publisher]
Source: Oncology Research - December 18, 2016 Category: Cancer & Oncology Tags: Oncol Res Source Type: research