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Cytorhabdovirus phosphoprotein shows RNA silencing suppressor activity in plants, but not in insect cells.
Abstract RNA silencing in plants and insects provides an antiviral defense and as a countermeasure most viruses encode RNA silencing suppressors (RSS). For the family Rhabdoviridae, no detailed functional RSS studies have been reported in plant hosts and insect vectors. In agroinfiltrated Nicotiana benthamiana leaves we show for the first time for a cytorhabdovirus, lettuce necrotic yellows virus (LNYV), that one of the nucleocapsid core proteins, phosphoprotein (P) has relatively weak local RSS activity and delays systemic silencing of a GFP reporter. Analysis of GFP small RNAs indicated that the P protein did no...
Source: Virology - January 12, 2015 Category: Virology Authors: Mann KS, Johnson KN, Dietzgen RG Tags: Virology Source Type: research