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Source: Cell Biology International
Cancer: Carcinoma
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Total 29 results found since Jan 2013.
miR-4443 targets TRIM14 to suppress metastasis and energy metabolism of papillary thyroid carcinoma (PTC) in vitro
This study was designed to investigate the relationship between miR-4443 and TRIM14 on metastasis and energy metabolism in PTC and the underlying mechanisms. To this end, human PTC cells (SW1736 and MZ-CRC-1) were transfected with a miR-4443 mimic or miR-4443 inhibitor + siRNA-TRIM14, and then dual luciferase assay, Transwell, Seahorse, and Western blot were performed to assess the function of miR-4443 and the underlying mechanism. We found that ectopic expression of miR-4443 inhibited PTC cell migration, invasion, ATP production, and aerobic glycolysis, while inhibition of miR-4443 had the opposite effect. miR-4443 direct...
Source: Cell Biology International - May 29, 2021 Category: Cytology Authors: Xiao-Ming Zuo Hai-Wen Sun Hong Fang Yun Wu Qun Shi Yi-Fan Yu Source Type: research
