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Source: Toxicology in Vitro
Drug: Propofol
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Total 4 results found since Jan 2013.
Propofol inhibits proliferation and migration of glioma cells by up-regulating lncRNA GAS5
Toxicol In Vitro. 2022 Jan 24:105321. doi: 10.1016/j.tiv.2022.105321. Online ahead of print.ABSTRACTPropofol has been documented to exhibit anti-tumor effects in cancers. However, the underlying mechanisms of its inhibition remain unclear. We conducted this study to investigate the effect of propofol on lncRNA GAS5 in glioma cells, and to probe the role of GAS5 in the anti-tumor effects of propofol. Human glioma cell line U251 were treated with propofol. Cell proliferation, migration, invasion, cell cycle and apoptosis were evaluated, and the expression of GAS5 was measured. After that, we knockdown the expression of GAS5 ...
Source: Toxicology in Vitro - January 27, 2022 Category: Toxicology Authors: Yan Cheng Lina Zheng Haiyun Wang Chenyi Yang Weiwei Zhang Source Type: research
