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Drug: SGLT2 Inhibitors
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Total 16 results found since Jan 2013.
Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion
Nature Medicine 21, 512 (2015).
doi:10.1038/nm.3828
Authors: Caroline Bonner, Julie Kerr-Conte, Valéry Gmyr, Gurvan Queniat, Ericka Moerman, Julien Thévenet, Cédric Beaucamps, Nathalie Delalleau, Iuliana Popescu, Willy J Malaisse, Abdullah Sener, Benoit Deprez, Amar Abderrahmani, Bart Staels & François Pattou
Type 2 diabetes (T2D) is characterized by chronic hyperglycemia resulting from a deficiency in insulin signaling, because of insulin resistance and/or defects in insulin secretion; it is also associated with increases in glucagon and endogenous glucose production (EGP). Gliflozins, incl...
Source: Nature Medicine - April 20, 2015 Category: Journals (General) Authors: Caroline BonnerJulie Kerr-ConteValéry GmyrGurvan QueniatEricka MoermanJulien ThévenetCédric BeaucampsNathalie DelalleauIuliana PopescuWilly J MalaisseAbdullah SenerBenoit DeprezAmar AbderrahmaniBart StaelsFrançois Pattou Tags: Letter Source Type: research
