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Where should siRNAs go: applicable organs for siRNA drugs
Experimental & Molecular Medicine, Published online: 10 July 2023; doi:10.1038/s12276-023-00998-yRefining the design and delivery of RNA-based drugs could improve the chances of targeting diseases in complex organs. Gene expression is regulated by small interfering RNAs (siRNAs), which bind to messenger RNA sequences, preventing subsequent gene expression. Drugs based on siRNA show promise as safe and specialised for multiple diseases. Jinju Han and co-workers at the Korea Advanced Institute for Science and Technology in Daejeon, South Korea, reviewed the current status of siRNA drugs. Five siRNAs approved by the US Fo...
Source: Experimental and Molecular Medicine - July 10, 2023 Category: Molecular Biology Authors: Insook Ahn Chanhee S. Kang Jinju Han Source Type: research
