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Condition: Atrial Fibrillation
Therapy: Statin Therapy
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Rac1 GTPase regulates 11{beta} hydroxysteroid dehydrogenase type 2 and fibrotic remodeling Molecular Bases of Disease
In conclusion, Rac1 GTPase regulates 11β-HSD2 expression, MR activation, and MR-mediated pro-fibrotic signaling.
Source: Journal of Biological Chemistry - May 5, 2017 Category: Chemistry Authors: Daniel Lavall, Pia Schuster, Nadine Jacobs, Andrey Kazakov, Michael Bohm, Ulrich Laufs Tags: Signal Transduction Source Type: research