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Specialty: Toxicology
Condition: Renal Failure
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Sialic Acid Rescues Repurified Lipopolysaccharide-Induced Acute Renal Failure via Inhibiting TLR4/PKC/gp91-Mediated Endoplasmic Reticulum Stress, Apoptosis, Autophagy, and Pyroptosis Signaling
In conclusion, early treatment (within 30 min) of SA attenuates rLPS-induced renal failure via the reduction in LPS toxicity and subsequently inhibiting rLPS-activated TLR4/PKC/gp91/ER stress/apoptosis/autophagy/pyroptosis signaling.
Source: Toxicological Sciences - September 17, 2014 Category: Toxicology Authors: Yang, C.-C., Yao, C.-A., Yang, J.-C., Chien, C.-T. Tags: Immunotoxicology Source Type: research
