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Source: Cell Research
Cancer: Bile Duct Cancer
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Total 2 results found since Jan 2013.
CD90 is regulated by notch1 and hallmarks a more aggressive intrahepatic cholangiocarcinoma phenotype
CONCLUSIONS: iCCA patients with higher NOTCH1/HES1/THY1 expression have the worst prognosis, but they are more likely to benefit from Notch signaling inhibition. These findings represent the scientific rationale for testing NOTCH1 inhibitors in clinical trials, taking the first step toward precision medicine for iCCA.PMID:35172861 | DOI:10.1186/s13046-022-02283-8
Source: Cell Research - February 17, 2022 Category: Cytology Authors: Serena Mancarella Grazia Serino Isabella Gigante Antonio Cigliano Silvia Ribback Paola Sanese Valentina Grossi Cristiano Simone Raffaele Armentano Matthias Evert Diego F Calvisi Gianluigi Giannelli Source Type: research
Exosomal p38 Mitogen-activated Protein Kinase Promotes Tumour Repopulation in < em > TP53 < /em > -mutated Bile Duct Cancer Cells
CONCLUSION: Exosomal p38 MAPK plays a pivotal role in tumour repopulation in a TP53-independent manner.PMID:35093873 | DOI:10.21873/anticanres.15533
Source: Cell Research - January 30, 2022 Category: Cytology Authors: Mami Osawa Yasunobu Matsuda Jun Sakata Toshifumi Wakai Source Type: research
