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Cancer: Bone Cancers
Drug: Hydrocortisone
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Total 2 results found since Jan 2013.
Thiram, an inhibitor of 11 ß-hydroxysteroid dehydrogenase type 2, enhances the inhibitory effects of hydrocortisone in the treatment of osteosarcoma through Wnt/β-catenin pathway
CONCLUSIONS: Hydrocortisone inhibits osteosarcoma through the Wnt/β-catenin pathway. Thiram inhibits 11HSD2 enzyme activity, reducing hydrocortisone inactivation and promoting the effect of hydrocortisone through the same pathway.PMID:36978114 | PMC:PMC10045229 | DOI:10.1186/s40360-023-00655-0
Source: BMC Pharmacology and Toxicology - March 28, 2023 Category: Drugs & Pharmacology Authors: You Zhang Nanjing Li He Li Maojia Chen Wei Jiang Wenhao Guo Source Type: research
