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Source: Advances in Cancer Research
Cancer: Carcinoma
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Total 106 results found since Jan 2013.
Astrocyte elevated gene-1 (AEG-1): A key driver of hepatocellular carcinoma (HCC)
Adv Cancer Res. 2021;152:329-381. doi: 10.1016/bs.acr.2021.05.003. Epub 2021 Jun 16.ABSTRACTAn array of human cancers, including hepatocellular carcinoma (HCC), overexpress the oncogene Astrocyte elevated gene-1 (AEG-1). It is now firmly established that AEG-1 is a key driver of carcinogenesis, and enhanced expression of AEG-1 is a marker of poor prognosis in cancer patients. In-depth studies have revealed that AEG-1 positively regulates different hallmarks of HCC progression including growth and proliferation, angiogenesis, invasion, migration, metastasis and resistance to therapeutic intervention. By interacting with a p...
Source: Advances in Cancer Research - August 6, 2021 Category: Cancer & Oncology Authors: Indranil Banerjee Paul B Fisher Devanand Sarkar Source Type: research
