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GIST (ILEAL) Revealed by Peculiar Paraneoplastic-myositis and Hypo-Thyroidism
CONCLUSION: Upto 10% dermato-myositis 5% poly-myositis can be paraneoplastic manifestation of underlying solid organ malignancy. overexpression of thyroid-hormone-inactivating type 3 iodothyronine deiodinase (D3) enzyme from GIST tumours often leads to hypothyroidism. References 1.Maynard MA, Marino-Enriquez A, Fletcher JA, et al. Thyroid hormone inactivation in gastrointestinal stromal tumors. N Engl J Med 2014;370:1327-1334. 2.Samimi M, Nseir A, Kerdraon R, et al. Tumeur stromale duodenale revelee par une dermatomyosite paranéoplasiqueStromal duodenal tumor revealed by paraneoplastic dermatomyositis. Gastroenterol Clin ...
Source: Journal of the Association of Physicians of India - April 28, 2023 Category: General Medicine Authors: Chirantan Mandal Pradeep Kumar Dutta Source Type: research
