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Brachio-cervical inflammatory myopathy associated with systemic sclerosis. Case series and review of literature
This study was aimed at describing a case series of brachio-cervical inflammatory myopathy (BCIM) associated with systemic sclerosis (SSc), due to its rarity and limited coverage in published data. Another aim was to provide a literature review. We reported four cases of BCIM-SSc from our tertiary center. In addition, we researched the literature and found six articles featuring 17 patients who fit this phenotype. We pooled all cases and reported their features. Most patients were female and had limited SSc, and the median time of BCIM presentation was three years after SSc diagnosis. Asymmetric muscle involvement, scapula...
Source: Reumatismo - August 3, 2021 Category: Rheumatology Authors: C S R Araujo R Miossi F H C De Souza M D Costa A M S Da Silva E D Campos E Zanoteli S K Shinjo Source Type: research

Histopathology of the muscle in rheumatic diseases.
Abstract The presence of muscular symptoms is common in rheumatological clinical practice, but often the differential diagnosis between muscular involvement in connective tissue diseases, vasculitis and drug-induced myopathy may be difficult. In addition to clinical assessment, laboratory analysis and instrumental examinations, muscle biopsy may help to clarify the diagnosis in patients with muscular involvement. The purpose of this review is to provide a critical analysis of the current medical literature on muscular histopathology, to help clinicians to identify when to perform muscular biopsy and to provide a p...
Source: Reumatismo - October 3, 2018 Category: Rheumatology Authors: Barsotti S, Tripoli A, Pollina LE, Mosca M, Neri R Tags: Reumatismo Source Type: research

Acute heart failure and rhabdomyolysis: a clue for the diagnosis of polymyositis with cardiac involvement.
We report the case of a 51-year-old male, with history of complete heart block, which required pacemaker implantation, and subsequently heart failure, presenting to the emergency department with worsening of dyspnea and peripheral edema. He was admitted to the Internal Medicine ward with acute heart failure and started on diuretic therapy. During hospitalization, he was discovered to have marked rhabdomyolysis. Examination revealed proximal symmetrical muscle weakness and arthralgia. The immunological study, electromyography and muscle biopsy confirmed polymyositis. The patient was started on prednisolone with clinical imp...
Source: Reumatismo - August 3, 2017 Category: Rheumatology Authors: Pinto-Lopes P, Carneiro-Leão L, Morais R, Pinheiro J, Vieira Lopes A, Bettencourt P Tags: Reumatismo Source Type: research

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