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The insidious impact of under-diagnosed proximal weakness induced by statins
Expert Rev Neurother. 2021 Mar;21(3):267-275. doi: 10.1080/14737175.2021.1866988. Epub 2020 Dec 24.ABSTRACTIntroduction: This Perspective reassesses the consensus opinion that statin-associated muscle symptoms (SAMS) occur in <1% of users and associated myopathic proximal muscle weakness is even more rare.Areas covered: Of the over 180,000 participants in clinical trials and large registries of statin users, only a few studies have included a standard manual muscle test (MMT), dynamometry or a focused questionnaire to assess for proximal weakness and related disability in daily and recreational activities. Formal streng...
Source: Expert Review of Neurotherapeutics - December 19, 2020 Category: Neurology Authors: Bruce H Dobkin Source Type: research
