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Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from < em > Origanum vulgare < /em > in alloxan-induced diabetic rats
This study evaluated the hypoglycemic activity of an infusion extract (RosCE) of commercially available O. vulgare leaves in alloxan-induced diabetic rats. Oral administration of RosCE resulted in the reduction of blood glucose levels after the first day of treatment, compared to the diabetic control group. These results showed that RosCE displays hypoglycemic activity, which may be due to the combined effect of rosmarinic acid, and other minor compounds. Reversed phase-high performance liquid chromatography-diode array detection was used to identify and quantify the major constituents of RosCE. This study presents evidenc...
Source: Natural Product Research - October 14, 2021 Category: Biochemistry Authors: M árcio L A E Silva Rodrigo Lucarini Fransergio F Dos Santos Carlos H G Martins Patricia M Pauletti Ana H Januario Mario Ferreira Concei ção Santos Wilson R Cunha Source Type: research