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Fight Aging! Newsletter, June 21st 2021
This study showed that the leakage of this mitochondrial nucleic material may occur as a result of mitochondrial dysfunction, which may involve genetic mutations in genes encoding mitochondrial proteins or incomplete degradation of mitochondrial dsDNA in the lysosome - which is a 'degradation factory' of the cell. Upon the leakage into the cytoplasm, this undegraded dsDNA is detected by a 'foreign' DNA sensor of the cytoplasm (IFI16) which then triggers the upregulation of mRNAs encoding for inflammatory proteins." Using a PD zebrafish model (gba mutant), the researchers demonstrated that a combination of PD-like ph...
Source: Fight Aging! - June 20, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Most Pressing Issues In Bioethics
Who owns medical and genetic data? How to regulate gene editing? Where is the boundary of enhancing physical or cognitive human capabilities? What to do with biological differences widening the gap of the haves and have-nots? Could we define where is the boundary to augment life? Will we sue robots or algorithms for medical malpractice? With the constant advancement of technology, unprecedented moral, ethical and legal concerns are surfacing. Channeling them into substantial debates will get us closer to their fair solution step by step. Here, we collected the most pressing issues in bioethics. Bioethicists of the world...
Source: The Medical Futurist - March 26, 2019 Category: Information Technology Authors: nora Tags: Bioethics Cyborgization Genomics bioethical data debate DNA future gene editing genetic genetics Innovation legal longevity medical medical data moral sex sexuality technology Source Type: blogs