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Source: European Review for Medical and Pharmacological Sciences

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Total 1317 results found since Jan 2013.

Factors affecting anxiety, depression, and stress among patients with hepatocellular carcinoma during COVID-19 pandemic
CONCLUSIONS: Chronic disease, gender, and age were prominent factors in predicting the DASS-21 total score in HCC patients. Therefore, the crucial factors were clinically considered for managing depression, stress, and anxiety in HCC patients.PMID:36734727 | DOI:10.26355/eurrev_202301_31073
Source: European Review for Medical and Pharmacological Sciences - February 3, 2023 Category: Drugs & Pharmacology Authors: S Akbulut M Tamer Z Kucukakcali M Akyuz H Saritas N Bagci F Ciftci M S Akbulut E Karabulut S Yilmaz Source Type: research

Nirmatrelvir increases blood tacrolimus concentration in COVID-19 patients as determined by UHPLC-MS/MS method
CONCLUSIONS: We developed a simple quantification method for therapeutic drug monitoring of FK506 in patients with COVID-19 using UHPLC-MS/MS with protein precipitation. We found that NMV increased FK506 blood concentration 10-fold. Therefore, it is necessary to re-consider co-administration of FK506 with NMV.PMID:36734723 | DOI:10.26355/eurrev_202301_31083
Source: European Review for Medical and Pharmacological Sciences - February 3, 2023 Category: Drugs & Pharmacology Authors: Q-G Wu L-Y Zeng F Li Z-Q Zhu L Yin X-M Meng L Zhang P Zhang X-H Jiang Y Ling L-J Zhang Source Type: research

Identification and development of a five-gene signature to improve the prediction of mechanical ventilator-free days for patients with COVID-19
CONCLUSIONS: This study identified a five-gene signature that can predict the length of ventilator-free days for patients with COVID-19.PMID:36734721 | DOI:10.26355/eurrev_202301_31082
Source: European Review for Medical and Pharmacological Sciences - February 3, 2023 Category: Drugs & Pharmacology Authors: J-X Ni Y-B Qian Y-W Zhang Source Type: research

Factors affecting anxiety, depression, and stress among patients with hepatocellular carcinoma during COVID-19 pandemic
CONCLUSIONS: Chronic disease, gender, and age were prominent factors in predicting the DASS-21 total score in HCC patients. Therefore, the crucial factors were clinically considered for managing depression, stress, and anxiety in HCC patients.PMID:36734727 | DOI:10.26355/eurrev_202301_31073
Source: European Review for Medical and Pharmacological Sciences - February 3, 2023 Category: Drugs & Pharmacology Authors: S Akbulut M Tamer Z Kucukakcali M Akyuz H Saritas N Bagci F Ciftci M S Akbulut E Karabulut S Yilmaz Source Type: research

Nirmatrelvir increases blood tacrolimus concentration in COVID-19 patients as determined by UHPLC-MS/MS method
CONCLUSIONS: We developed a simple quantification method for therapeutic drug monitoring of FK506 in patients with COVID-19 using UHPLC-MS/MS with protein precipitation. We found that NMV increased FK506 blood concentration 10-fold. Therefore, it is necessary to re-consider co-administration of FK506 with NMV.PMID:36734723 | DOI:10.26355/eurrev_202301_31083
Source: European Review for Medical and Pharmacological Sciences - February 3, 2023 Category: Drugs & Pharmacology Authors: Q-G Wu L-Y Zeng F Li Z-Q Zhu L Yin X-M Meng L Zhang P Zhang X-H Jiang Y Ling L-J Zhang Source Type: research

Identification and development of a five-gene signature to improve the prediction of mechanical ventilator-free days for patients with COVID-19
CONCLUSIONS: This study identified a five-gene signature that can predict the length of ventilator-free days for patients with COVID-19.PMID:36734721 | DOI:10.26355/eurrev_202301_31082
Source: European Review for Medical and Pharmacological Sciences - February 3, 2023 Category: Drugs & Pharmacology Authors: J-X Ni Y-B Qian Y-W Zhang Source Type: research

The effect of hereditary thrombotic factors and comorbidities on the severity of COVID-19 disease
CONCLUSIONS: The presence of solid tumors in patients with COVID-19 was related to the severity of the disease course. No evidence of a correlation between the severity of the disease and all five thrombotic mutations was found, whereas the FII G20210A and Beta-fibrinogen G-455A mutations were significantly high compared to previously reported Turkish population data and global carrier rates. This finding will need to be verified by further studies with larger samples since it may reflect a likelihood of having the COVID-19 disease. The high carrier frequency of FVL mutation was more likely present in the D-dimer high grou...
Source: European Review for Medical and Pharmacological Sciences - January 17, 2023 Category: Drugs & Pharmacology Authors: M Kose N Senkal H Konyaoglu A Emet Y Oyaci S Pehlivan G Y Sayin Source Type: research

Development and validation of COVID-19 Radiological Risk Score (COVID-RRS): a multivariable radiological score to estimate the in-hospital mortality risk in COVID-19 patients
CONCLUSIONS: Additional imaging features independently contribute to COVID-19 mortality risk. Our model comprising lung involvement estimation, pleural effusion, and domination of consolidations performed significantly better than scores based on the extent of the changes alone. COVID-RRS is a simple, reliable, and ready-to-use tool for clinical practice.PMID:36647887 | DOI:10.26355/eurrev_202301_30892
Source: European Review for Medical and Pharmacological Sciences - January 17, 2023 Category: Drugs & Pharmacology Authors: W Schmidt K Pawlak-Bu ś B J óźwiak K Katulska P Leszczy ński Source Type: research

Is chlorhexidine mouthwash effective in lowering COVID-19 viral load? A systematic review
CONCLUSIONS: Despite differences in the published research, CHX at different concentrations may be effective in lowering the SARS-COV-2 viral load in saliva.PMID:36647885 | DOI:10.26355/eurrev_202301_30890
Source: European Review for Medical and Pharmacological Sciences - January 17, 2023 Category: Drugs & Pharmacology Authors: G S Rahman A A N Alshetan S S O Alotaibi B M I Alaskar M A Baseer Source Type: research

The effect of hereditary thrombotic factors and comorbidities on the severity of COVID-19 disease
CONCLUSIONS: The presence of solid tumors in patients with COVID-19 was related to the severity of the disease course. No evidence of a correlation between the severity of the disease and all five thrombotic mutations was found, whereas the FII G20210A and Beta-fibrinogen G-455A mutations were significantly high compared to previously reported Turkish population data and global carrier rates. This finding will need to be verified by further studies with larger samples since it may reflect a likelihood of having the COVID-19 disease. The high carrier frequency of FVL mutation was more likely present in the D-dimer high grou...
Source: European Review for Medical and Pharmacological Sciences - January 17, 2023 Category: Drugs & Pharmacology Authors: M Kose N Senkal H Konyaoglu A Emet Y Oyaci S Pehlivan G Y Sayin Source Type: research

Development and validation of COVID-19 Radiological Risk Score (COVID-RRS): a multivariable radiological score to estimate the in-hospital mortality risk in COVID-19 patients
CONCLUSIONS: Additional imaging features independently contribute to COVID-19 mortality risk. Our model comprising lung involvement estimation, pleural effusion, and domination of consolidations performed significantly better than scores based on the extent of the changes alone. COVID-RRS is a simple, reliable, and ready-to-use tool for clinical practice.PMID:36647887 | DOI:10.26355/eurrev_202301_30892
Source: European Review for Medical and Pharmacological Sciences - January 17, 2023 Category: Drugs & Pharmacology Authors: W Schmidt K Pawlak-Bu ś B J óźwiak K Katulska P Leszczy ński Source Type: research

Is chlorhexidine mouthwash effective in lowering COVID-19 viral load? A systematic review
CONCLUSIONS: Despite differences in the published research, CHX at different concentrations may be effective in lowering the SARS-COV-2 viral load in saliva.PMID:36647885 | DOI:10.26355/eurrev_202301_30890
Source: European Review for Medical and Pharmacological Sciences - January 17, 2023 Category: Drugs & Pharmacology Authors: G S Rahman A A N Alshetan S S O Alotaibi B M I Alaskar M A Baseer Source Type: research

Ginkgolides and bilobalide for treatment of Alzheimer's disease and COVID-19: potential mechanisms of action
Eur Rev Med Pharmacol Sci. 2022 Dec;26(24):9502-9510. doi: 10.26355/eurrev_202212_30702.ABSTRACTAlzheimer's disease (AD) is an irreversible degenerative illness of the central nervous system with characteristic histological alterations, known as amyloid plaques and neurofibrillary tangles (NFT). Aggregation of plaques and tangles in the brain induces neurotoxicity and synaptic dysfunction, eventually contributing to neuronal cell death and neurodegeneration. Recent studies have revealed that COVID-19 has a great impact on the development of AD, directly or indirectly, by facilitating the accumulation of amyloid plaques, ca...
Source: European Review for Medical and Pharmacological Sciences - January 2, 2023 Category: Drugs & Pharmacology Authors: T-T Niu B-Y Yuan G-Z Liu Source Type: research

Effects of oxygen saturation on the hypoxia-inducible factor-1 α, subfatin, asprosin, irisin, c-reactive protein, maresin-1, and diamine oxidase in diabetic patients with COVID-19
CONCLUSIONS: Changes in these molecules in patients with coronavirus and diabetes according to their oxygen saturation suggested that they functioned as the "metabolic oxygen sensors" of the metabolism. Therefore, according to these data, it was predicted that these molecules had the potential to be used in the diagnosis and follow-up of diseases related to oxygen (such as asthma, and critical intensive care patients) in clinics in the future.PMID:36591859 | DOI:10.26355/eurrev_202212_30701
Source: European Review for Medical and Pharmacological Sciences - January 2, 2023 Category: Drugs & Pharmacology Authors: Z Karaca Karagoz S Aydin Source Type: research

Ginkgolides and bilobalide for treatment of Alzheimer's disease and COVID-19: potential mechanisms of action
Eur Rev Med Pharmacol Sci. 2022 Dec;26(24):9502-9510. doi: 10.26355/eurrev_202212_30702.ABSTRACTAlzheimer's disease (AD) is an irreversible degenerative illness of the central nervous system with characteristic histological alterations, known as amyloid plaques and neurofibrillary tangles (NFT). Aggregation of plaques and tangles in the brain induces neurotoxicity and synaptic dysfunction, eventually contributing to neuronal cell death and neurodegeneration. Recent studies have revealed that COVID-19 has a great impact on the development of AD, directly or indirectly, by facilitating the accumulation of amyloid plaques, ca...
Source: European Review for Medical and Pharmacological Sciences - January 2, 2023 Category: Drugs & Pharmacology Authors: T-T Niu B-Y Yuan G-Z Liu Source Type: research