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Recent advances in the vaccine development for the prophylaxis of SARS Covid-19
Int Immunopharmacol. 2022 Aug 17;111:109175. doi: 10.1016/j.intimp.2022.109175. Online ahead of print.ABSTRACTThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-caused Coronavirus Disease 2019 (COVID-19) is currently a global pandemic that has wreaked havoc on public health, lives, and the global economy. The present COVID-19 outbreak has put pressure on the scientific community to develop medications and vaccinations to combat COVID-19. However, according to highly optimistic forecasts, we could not have a COVID-19 vaccine until September 2020. This is due to the fact that a successful COVID-19 vaccine will ...
Source: International Immunopharmacology - August 22, 2022 Category: Allergy & Immunology Authors: Vipul Kumar Sahil Kumar Prabodh Chander Sharma Source Type: research

Test of a Homeopathic Algorithm for COVID-19: the Importance of a Broad Perspective
CONCLUSION: The Bayesian mini-repertory and app is based on qualitative clinical experiences of various doctors in COVID-19 and gives indications for specific medicines for common COVID-19 symptoms. It is freely available [English: https://hpra.co.uk/; Spanish: https://hpra.co.uk/es ] for further testing and utilization by the profession.PMID:35988581 | DOI:10.1055/s-0042-1746196
Source: Homeopathy - August 21, 2022 Category: Complementary Medicine Authors: Anjali Miglani Raj Kumar Manchanda Amrit Kalsi Prabhjeet Kaur Beenu Saini Amit Arora Cheshta Nagrath Jithesh Thavarayil Kannoth Ram Kumar Kudiyarasu Rahul Vardaan Smita Brahmachari Ankit Gupta Shelly Arora Shirin Balan Kavita Sharma Malaya Kumar Ray Anu C Source Type: research

IJERPH, Vol. 19, Pages 10421: Impact of COVID-19 on Health-Related Quality of Life: A Longitudinal Study in a Spanish Clinical Sample
Conclusions: COVID-19 pneumonia causes a long-term deterioration in HRQoL compared to the general population. Over time, a trend toward improvement is detected in most domains of the SF-36.
Source: International Journal of Environmental Research and Public Health - August 21, 2022 Category: Environmental Health Authors: Irene Rodr íguez-Galán Natalia Albaladejo-Bl ázquez Nicol ás Ruiz-Robledillo Jos é Francisco Pascual-Lledó Rosario Ferrer-Cascales Joan Gil-Carbonell Tags: Article Source Type: research

Potential of FX06 to prevent disease progression in hospitalized non-intubated COVID-19 patients — the randomized, EU-wide, placebo-controlled, phase II study design of IXION
DiscussionWith IXION, the multidisciplinary consortium aims to deliver a new therapy in addition to standard care against SARS-CoV-2 for the clinical management of COVID-19 during mild and moderate stages. Potential limitations might refer to a lack of recruiting and drop-out due to various possible protocol violations. While we controlled for drop-outs in the same size estimation, recruitment problems may be subject to external problems difficult to control for.Trial registrationEudraCT2021-005059-35. Registered on 12 December 2021. Study Code TMP-2204-2021-47.
Source: Trials - August 19, 2022 Category: Research Source Type: clinical trials

Where did the pandemic start? Anywhere but here, argue papers by Chinese scientists echoing party line
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Source: Science of Aging Knowledge Environment - August 18, 2022 Category: Geriatrics Source Type: research

Correspondence on: 'Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 mimicking Kawasaki disease (Kawa-COVID-19): a multicentre cohort by Pouletty et al
We report a prospective case series of paediatric patients that fulfilled clinical diagnostic criteria of KD during the SARS-CoV-2 pandemic in a paediatric referral centre in Barcelona, Spain. KD was defined according to the 2017 criteria of the American Heart Association.6 Assessment of SARS-CoV-2 infection was made by means of quantitative real-time PCR assay (GeneFinder COVID-19 Plus, Elitech; Puteaux, France) in nasopharyngeal samples; stools were tested in patients with diarrhoea. SARS-CoV-2 IgG qualitative determination (SARS-CoV-2 IgG chemiluminescent microparticle immunoassay; Abbot, Chicago, Illinois) was performe...
Source: Annals of the Rheumatic Diseases - August 11, 2022 Category: Rheumatology Authors: Pino, R., Izurieta, A. C., Rios-Barnes, M., Ricart, S., De Sevilla, M. F., Monfort, L., Launes, C., Cano, I., Lecina, L., Sanchez Manubens, J., Mosquera, J. M., Jordan, I., Sanchez de Toledo, J., Monsonis, M., Esteva, C., Munoz-Almagro, C., Fumado, V., Fo Tags: ARD, COVID-19 Correspondence Source Type: research

Response to: 'Correspondence on 'Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 mimicking Kawasaki disease (Kawa-COVID-19): a multicentre cohort by Pouletty et al by Pino et al
In their correspondence, Pino et al1 reported a cohort of 12 children with Kawasaki disease (KD) during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic in Barcelona, Spain. Among them, six had a positive SARS-CoV-2 infection confirmed by RT-PCR or serology while six had not. Interestingly, in line with our findings2 and reports from other settings,3–7 patients with multisystem inflammatory syndrome temporally associated with SARS-CoV-2 infection mimicking KD (Kawa-COVID-19) exhibited several differences as compared with classical KD, such as older age, higher inflammatory parameters, more fr...
Source: Annals of the Rheumatic Diseases - August 11, 2022 Category: Rheumatology Authors: Ouldali, N., Pouletty, M., Lokmer, J., Benzouid, C., Beyler, C., Deho, A., Meinzer, U., Faye, A., Melki, I., Great Paris Region (GPR) Kawa-COVID-19 consortium, Borocco, Caseris, Basmaci, Lachaume, Bensaid, Pichard, Kouider, Morelle, Craiu, Pondarre, Maron Tags: ARD, COVID-19 Correspondence response Source Type: research