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Health Status and Inconveniences of Asthmatic Children During the First Year of the COVID-19 Pandemic
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):245-253. doi: 10.18502/ijaai.v22i3.13052.ABSTRACTThe Coronavirus Disease 2019 (COVID-19) pandemic has been the most significant health concern in recent years, with respiratory symptoms being the most prominent. In children, asthma is the most prevalent chronic disease. Due to the similarities between the symptoms of these two conditions, we sought to assess the general health status of pediatric patients with asthma and their COVID-19-related difficulties during the first year of the pandemic in Iran. We collected data for this study by administering a questionnaire to the ...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Saber Gharagozlou Negin Rostamzadeh Mohammad Gharagozlou Source Type: research
Exosomes from Adipose Tissue-derived Mesenchymal Stem Cells Induce Regulatory T Cells in COVID-19 Patients
This study aimed to assess the effect of MSC-derived exosomes (MSC-Exo) on the differentiation of peripheral blood mononuclear cells (PBMCs) into Tregs from patients with COVID-19. Exosomes were isolated from adipose tissue-derived MSCs. PBMCs were separated from the whole blood of COVID-19 patients (n=20). Treg frequency was assessed before and 48 hours after treatment of PBMCs with MSC-Exo using flow cytometry. Expression of FOXP3 and cytokine genes, and the concentration of cytokines associated with Tregs, were assessed before and after treatment with MSC-Exo. The frequency of CD4+CD25+CD127- Tregs was significantly hig...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Morteza Motallebnezhad Ali Hazrati Hadi Esmaeili Gouvarchin Ghaleh Nematollah Jonaidi-Jafari Sanaz Abbaspour-Aghdam Kosar Malekpour Mehdi Yousefi Hossein Samadi Kafil Farhad Jadidi-Niaragh Leila Roshangar Hamed Valizadeh Morteza Izadi Majid Ahmadi Source Type: research
Immune Profiling of SARS-CoV-2; What We Know and What We Don't Know
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):217-232. doi: 10.18502/ijaai.v22i3.13050.ABSTRACTCoronavirus disease 2019 (COVID-19), described as World War 3, is the current worldwide health challenge and nearly all countries have so far faced this disaster. There is still no cure because of the complicated pathogenesis, however, there are several studies on track investigating different aspects of the immune response to the virus. In this review, we will provide an overview of recent investigations that have analyzed immune cells in patients with COVID-19. We will then discuss the differences in immune profiles between ...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Mahshid Zohouri Atri Ghods Mina Roshan Zamir Fazel Shokri Abbas Ghaderi Source Type: research
Health Status and Inconveniences of Asthmatic Children During the First Year of the COVID-19 Pandemic
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):245-253. doi: 10.18502/ijaai.v22i3.13052.ABSTRACTThe Coronavirus Disease 2019 (COVID-19) pandemic has been the most significant health concern in recent years, with respiratory symptoms being the most prominent. In children, asthma is the most prevalent chronic disease. Due to the similarities between the symptoms of these two conditions, we sought to assess the general health status of pediatric patients with asthma and their COVID-19-related difficulties during the first year of the pandemic in Iran. We collected data for this study by administering a questionnaire to the ...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Saber Gharagozlou Negin Rostamzadeh Mohammad Gharagozlou Source Type: research
Exosomes from Adipose Tissue-derived Mesenchymal Stem Cells Induce Regulatory T Cells in COVID-19 Patients
This study aimed to assess the effect of MSC-derived exosomes (MSC-Exo) on the differentiation of peripheral blood mononuclear cells (PBMCs) into Tregs from patients with COVID-19. Exosomes were isolated from adipose tissue-derived MSCs. PBMCs were separated from the whole blood of COVID-19 patients (n=20). Treg frequency was assessed before and 48 hours after treatment of PBMCs with MSC-Exo using flow cytometry. Expression of FOXP3 and cytokine genes, and the concentration of cytokines associated with Tregs, were assessed before and after treatment with MSC-Exo. The frequency of CD4+CD25+CD127- Tregs was significantly hig...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Morteza Motallebnezhad Ali Hazrati Hadi Esmaeili Gouvarchin Ghaleh Nematollah Jonaidi-Jafari Sanaz Abbaspour-Aghdam Kosar Malekpour Mehdi Yousefi Hossein Samadi Kafil Farhad Jadidi-Niaragh Leila Roshangar Hamed Valizadeh Morteza Izadi Majid Ahmadi Source Type: research
Immune Profiling of SARS-CoV-2; What We Know and What We Don't Know
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):217-232. doi: 10.18502/ijaai.v22i3.13050.ABSTRACTCoronavirus disease 2019 (COVID-19), described as World War 3, is the current worldwide health challenge and nearly all countries have so far faced this disaster. There is still no cure because of the complicated pathogenesis, however, there are several studies on track investigating different aspects of the immune response to the virus. In this review, we will provide an overview of recent investigations that have analyzed immune cells in patients with COVID-19. We will then discuss the differences in immune profiles between ...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Mahshid Zohouri Atri Ghods Mina Roshan Zamir Fazel Shokri Abbas Ghaderi Source Type: research
Health Status and Inconveniences of Asthmatic Children During the First Year of the COVID-19 Pandemic
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):245-253. doi: 10.18502/ijaai.v22i3.13052.ABSTRACTThe Coronavirus Disease 2019 (COVID-19) pandemic has been the most significant health concern in recent years, with respiratory symptoms being the most prominent. In children, asthma is the most prevalent chronic disease. Due to the similarities between the symptoms of these two conditions, we sought to assess the general health status of pediatric patients with asthma and their COVID-19-related difficulties during the first year of the pandemic in Iran. We collected data for this study by administering a questionnaire to the ...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Saber Gharagozlou Negin Rostamzadeh Mohammad Gharagozlou Source Type: research
Exosomes from Adipose Tissue-derived Mesenchymal Stem Cells Induce Regulatory T Cells in COVID-19 Patients
This study aimed to assess the effect of MSC-derived exosomes (MSC-Exo) on the differentiation of peripheral blood mononuclear cells (PBMCs) into Tregs from patients with COVID-19. Exosomes were isolated from adipose tissue-derived MSCs. PBMCs were separated from the whole blood of COVID-19 patients (n=20). Treg frequency was assessed before and 48 hours after treatment of PBMCs with MSC-Exo using flow cytometry. Expression of FOXP3 and cytokine genes, and the concentration of cytokines associated with Tregs, were assessed before and after treatment with MSC-Exo. The frequency of CD4+CD25+CD127- Tregs was significantly hig...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Morteza Motallebnezhad Ali Hazrati Hadi Esmaeili Gouvarchin Ghaleh Nematollah Jonaidi-Jafari Sanaz Abbaspour-Aghdam Kosar Malekpour Mehdi Yousefi Hossein Samadi Kafil Farhad Jadidi-Niaragh Leila Roshangar Hamed Valizadeh Morteza Izadi Majid Ahmadi Source Type: research
Immune Profiling of SARS-CoV-2; What We Know and What We Don't Know
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):217-232. doi: 10.18502/ijaai.v22i3.13050.ABSTRACTCoronavirus disease 2019 (COVID-19), described as World War 3, is the current worldwide health challenge and nearly all countries have so far faced this disaster. There is still no cure because of the complicated pathogenesis, however, there are several studies on track investigating different aspects of the immune response to the virus. In this review, we will provide an overview of recent investigations that have analyzed immune cells in patients with COVID-19. We will then discuss the differences in immune profiles between ...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Mahshid Zohouri Atri Ghods Mina Roshan Zamir Fazel Shokri Abbas Ghaderi Source Type: research
Health Status and Inconveniences of Asthmatic Children During the First Year of the COVID-19 Pandemic
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):245-253. doi: 10.18502/ijaai.v22i3.13052.ABSTRACTThe Coronavirus Disease 2019 (COVID-19) pandemic has been the most significant health concern in recent years, with respiratory symptoms being the most prominent. In children, asthma is the most prevalent chronic disease. Due to the similarities between the symptoms of these two conditions, we sought to assess the general health status of pediatric patients with asthma and their COVID-19-related difficulties during the first year of the pandemic in Iran. We collected data for this study by administering a questionnaire to the ...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Saber Gharagozlou Negin Rostamzadeh Mohammad Gharagozlou Source Type: research
Exosomes from Adipose Tissue-derived Mesenchymal Stem Cells Induce Regulatory T Cells in COVID-19 Patients
This study aimed to assess the effect of MSC-derived exosomes (MSC-Exo) on the differentiation of peripheral blood mononuclear cells (PBMCs) into Tregs from patients with COVID-19. Exosomes were isolated from adipose tissue-derived MSCs. PBMCs were separated from the whole blood of COVID-19 patients (n=20). Treg frequency was assessed before and 48 hours after treatment of PBMCs with MSC-Exo using flow cytometry. Expression of FOXP3 and cytokine genes, and the concentration of cytokines associated with Tregs, were assessed before and after treatment with MSC-Exo. The frequency of CD4+CD25+CD127- Tregs was significantly hig...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Morteza Motallebnezhad Ali Hazrati Hadi Esmaeili Gouvarchin Ghaleh Nematollah Jonaidi-Jafari Sanaz Abbaspour-Aghdam Kosar Malekpour Mehdi Yousefi Hossein Samadi Kafil Farhad Jadidi-Niaragh Leila Roshangar Hamed Valizadeh Morteza Izadi Majid Ahmadi Source Type: research
Immune Profiling of SARS-CoV-2; What We Know and What We Don't Know
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):217-232. doi: 10.18502/ijaai.v22i3.13050.ABSTRACTCoronavirus disease 2019 (COVID-19), described as World War 3, is the current worldwide health challenge and nearly all countries have so far faced this disaster. There is still no cure because of the complicated pathogenesis, however, there are several studies on track investigating different aspects of the immune response to the virus. In this review, we will provide an overview of recent investigations that have analyzed immune cells in patients with COVID-19. We will then discuss the differences in immune profiles between ...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Mahshid Zohouri Atri Ghods Mina Roshan Zamir Fazel Shokri Abbas Ghaderi Source Type: research
Exosomes from Adipose Tissue-derived Mesenchymal Stem Cells Induce Regulatory T Cells in COVID-19 Patients
This study aimed to assess the effect of MSC-derived exosomes (MSC-Exo) on the differentiation of peripheral blood mononuclear cells (PBMCs) into Tregs from patients with COVID-19. Exosomes were isolated from adipose tissue-derived MSCs. PBMCs were separated from the whole blood of COVID-19 patients (n=20). Treg frequency was assessed before and 48 hours after treatment of PBMCs with MSC-Exo using flow cytometry. Expression of FOXP3 and cytokine genes, and the concentration of cytokines associated with Tregs, were assessed before and after treatment with MSC-Exo. The frequency of CD4+CD25+CD127- Tregs was significantly hig...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Morteza Motallebnezhad Ali Hazrati Hadi Esmaeili Gouvarchin Ghaleh Nematollah Jonaidi-Jafari Sanaz Abbaspour-Aghdam Kosar Malekpour Mehdi Yousefi Hossein Samadi Kafil Farhad Jadidi-Niaragh Leila Roshangar Hamed Valizadeh Morteza Izadi Majid Ahmadi Source Type: research
Immune Profiling of SARS-CoV-2; What We Know and What We Don't Know
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):217-232. doi: 10.18502/ijaai.v22i3.13050.ABSTRACTCoronavirus disease 2019 (COVID-19), described as World War 3, is the current worldwide health challenge and nearly all countries have so far faced this disaster. There is still no cure because of the complicated pathogenesis, however, there are several studies on track investigating different aspects of the immune response to the virus. In this review, we will provide an overview of recent investigations that have analyzed immune cells in patients with COVID-19. We will then discuss the differences in immune profiles between ...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Mahshid Zohouri Atri Ghods Mina Roshan Zamir Fazel Shokri Abbas Ghaderi Source Type: research
