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A practical approach to the ESC 2022 cardio-oncology guidelines. Comments by a team of experts: cardiologists and oncologists
Kardiol Pol. 2023 Sep 3. doi: 10.33963/v.kp.96840. Online ahead of print.ABSTRACTThe 2022 European Society of Cardiology (ESC) guidelines [1] are a comprehensive document, prepared jointly by experts in cardiology and oncology. In the case of an oncological patient, it is necessary to individualize care in relation to the cardiological condition, the stage of the cancer and the type of potential anti-cancer therapy. Cardiac care optimisation should be undertaken before the start of oncological therapy, and continued during oncological therapy, as well as long-term after its completion [2]. The published ESC Guidelines were...
Source: Kardiologia Polska - September 3, 2023 Category: Cardiology Authors: Przemys ław Leszek Aneta Klotzka Stanis ław Bartuś Pawe ł Burchardt Anna M Czarnecka Monika D ługosz-Danecka Marek Gierlotka Hanna Kose ła-Paterczyk Agata Krawczyk-O żóg Tomasz Kubiatowski Marcin Kurzyna Adam Maciejczyk Przemys ław Mitkowski Alek Source Type: research

Subverted macrophages in the triple-negative breast cancer ecosystem
Biomed Pharmacother. 2023 Sep 1;166:115414. doi: 10.1016/j.biopha.2023.115414. Online ahead of print.ABSTRACTTumor-associated macrophages (TAMs) are the most critical effector cells of innate immunity and the most abundant tumor-infiltrating immune cells. They play a key role in the clearance of apoptotic bodies, regulation of inflammation, and tissue repair to maintain homeostasis in vivo. With the progression of triple-negative breast cancer(TNBC), TAMs are "subverted" from tumor-promoting immune cells to tumor-promoting immune suppressor cells, which play a significant role in tumor development and are considered po...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 3, 2023 Category: Drugs & Pharmacology Authors: Linxiao Shang Yuting Zhong Yan Yao Cun Liu Lu Wang Wenfeng Zhang Jingyang Liu Xue Wang Changgang Sun Source Type: research

Collagen code in tumor microenvironment: Functions, molecular mechanisms, and therapeutic implications
Biomed Pharmacother. 2023 Sep 1;166:115390. doi: 10.1016/j.biopha.2023.115390. Online ahead of print.ABSTRACTThe tumor microenvironment (TME) is crucial in cancer progression, and the extracellular matrix (ECM) is an important TME component. Collagen is a major ECM component that contributes to tumor cell infiltration, expansion, and distant metastasis during cancer progression. Recent studies reported that collagen is deposited in the TME to form a collagen wall along which tumor cells can infiltrate and prevent drugs from working on the tumor cells. Collagen-tumor cell interaction is complex and requires the activation o...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 3, 2023 Category: Drugs & Pharmacology Authors: Qian Zhang Zi-Yi An Wen Jiang Wei-Lin Jin Xin-Yang He Source Type: research

A practical approach to the ESC 2022 cardio-oncology guidelines. Comments by a team of experts: cardiologists and oncologists
Kardiol Pol. 2023 Sep 3. doi: 10.33963/v.kp.96840. Online ahead of print.ABSTRACTThe 2022 European Society of Cardiology (ESC) guidelines [1] are a comprehensive document, prepared jointly by experts in cardiology and oncology. In the case of an oncological patient, it is necessary to individualize care in relation to the cardiological condition, the stage of the cancer and the type of potential anti-cancer therapy. Cardiac care optimisation should be undertaken before the start of oncological therapy, and continued during oncological therapy, as well as long-term after its completion [2]. The published ESC Guidelines were...
Source: Polish Heart Journal - September 3, 2023 Category: Cardiology Authors: Przemys ław Leszek Aneta Klotzka Stanis ław Bartuś Pawe ł Burchardt Anna M Czarnecka Monika D ługosz-Danecka Marek Gierlotka Hanna Kose ła-Paterczyk Agata Krawczyk-O żóg Tomasz Kubiatowski Marcin Kurzyna Adam Maciejczyk Przemys ław Mitkowski Alek Source Type: research

Role of cancer-educated mesenchymal stromal cells on tumor progression
Biomed Pharmacother. 2023 Sep 1;166:115405. doi: 10.1016/j.biopha.2023.115405. Online ahead of print.ABSTRACTThe malignant tumor is the main cause of human deaths worldwide. Current therapies focusing on the tumor itself have achieved unprecedented benefits. Various pro-tumorigenic factors in the tumor microenvironment (TME) could abolish the effect of cancer therapy. Mesenchymal stromal cells (MSCs) are one of the substantial components in the tumor microenvironment, contributing to tumor progression. However, MSCs are not inherently tumor-promoting. Indeed, they acquire pro-tumorigenic properties under the education of t...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 3, 2023 Category: Drugs & Pharmacology Authors: Ting Liu Shuwei Guo Yong Ji Wei Zhu Source Type: research

A practical approach to the ESC 2022 cardio-oncology guidelines. Comments by a team of experts: cardiologists and oncologists
Kardiol Pol. 2023 Sep 3. doi: 10.33963/v.kp.96840. Online ahead of print.ABSTRACTThe 2022 European Society of Cardiology (ESC) guidelines [1] are a comprehensive document, prepared jointly by experts in cardiology and oncology. In the case of an oncological patient, it is necessary to individualize care in relation to the cardiological condition, the stage of the cancer and the type of potential anti-cancer therapy. Cardiac care optimisation should be undertaken before the start of oncological therapy, and continued during oncological therapy, as well as long-term after its completion [2]. The published ESC Guidelines were...
Source: Kardiologia Polska - September 3, 2023 Category: Cardiology Authors: Przemys ław Leszek Aneta Klotzka Stanis ław Bartuś Pawe ł Burchardt Anna M Czarnecka Monika D ługosz-Danecka Marek Gierlotka Hanna Kose ła-Paterczyk Agata Krawczyk-O żóg Tomasz Kubiatowski Marcin Kurzyna Adam Maciejczyk Przemys ław Mitkowski Alek Source Type: research