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Therapy: Chemotherapy

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After Chemotherapy Treatment for Maternal Cancer During Pregnancy, Is Breastfeeding Possible?
Breastfeeding Medicine , Vol. 0, No. 0.
Source: Breastfeeding Medicine - February 6, 2017 Category: Perinatology & Neonatology Authors: Stephen Stopenski Anum Aslam Xinmin Zhang Elyce Cardonick Source Type: research

Presence of 5 chemotherapeutic drugs in breast milk as a guide for the safe use of chemotherapy during breastfeeding: results from a case series
Clin Pharmacol Ther. 2022 Apr 29. doi: 10.1002/cpt.2626. Online ahead of print.ABSTRACTLittle is known about infant's safety of chemotherapy during breastfeeding where evidence is limited to few case reports. This lack of knowledge has led to a general tendency to advice against breastfeeding during cytotoxic therapy despite the overwhelming benefits that breastfeeding offers to both the mother and their children. In this case series, the presence of 5 chemotherapies in breast milk was determined. The aim was to obtain insight into the presence of these drugs in breast milk to inform and help clinicians in making informed ...
Source: Clinical Breast Cancer - April 29, 2022 Category: Cancer & Oncology Authors: David Damoiseaux Silvia Calpe Hilde Rosing Jos H Beijnen Alwin D R Huitema Christianne Lok Thomas P C Dorlo Fr édéric Amant Source Type: research

Predicting Chemotherapy Distribution into Breast Milk for Breastfeeding Women Using a Population Pharmacokinetic Approach
CONCLUSION: Our results may help clinicians to derive the optimal breast milk discarding strategy for an individual patient that wants to breastfeed during chemotherapy and minimize chemotherapy exposure in their infants.PMID:37154994 | DOI:10.1007/s40262-023-01251-5
Source: Clinical Breast Cancer - May 8, 2023 Category: Cancer & Oncology Authors: David Damoiseaux Daniel Centanni Jos H Beijnen Fr édéric Amant Alwin D R Huitema Thomas P C Dorlo Source Type: research

Antibiotics and Breastfeeding
This article provides information on the main antibiotics that are appropriate for clinical use and the interference of these antibiotics with the infant to support medical decisions regarding the discontinuation of breastfeeding. We aim to provide information on the pharmacokinetic factors that interfere with the passage of antibiotics into breast milk and the toxicological implications of absorption by the infant. Publications related to the 20 most frequently employed antibiotics and their transfer into breast milk were evaluated. The results demonstrate that most antibiotics in clinical use are considered suitable duri...
Source: Chemotherapy - January 18, 2016 Category: Cancer & Oncology Source Type: research

Chemotherapy, targeted agents, antiemetics and growth-factors in human milk: How should we counsel cancer patients about breastfeeding?
Abstract: An increasing number of women are diagnosed with cancer during pregnancy and lactation. Women are usually advised to interrupt breastfeeding during systemic anticancer treatment for fear of serious adverse effects to the nursed infant. However, the issue is poorly addressed in the literature and very few studies have evaluated the safety of breastfeeding during or after cytotoxic drugs or target agents administration. In this review we will analyze the available evidence that addresses the issue of anticancer drugs, targeted agents, antiemetics and growth-factors excretion in human milk. This could serve as a uni...
Source: Cancer Treatment Reviews - November 30, 2012 Category: Cancer & Oncology Authors: Barbara Pistilli, Giulia Bellettini, Elisa Giovannetti, Giovanni Codacci-Pisanelli, Hatem A. Azim, Giovanni Benedetti, Maria Anna Sarno, Fedro A. Peccatori Tags: Hot Topics Source Type: research