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Total 73495 results found since Jan 2013.

Dietary palm oil enhances SREBP2-mediated cholesterol biosynthesis through inducing endoplasmic reticulum stress in muscle of large yellow croaker ( < em > Larimichthys crocea < /em > )
Br J Nutr. 2023 Sep 13:1-27. doi: 10.1017/S0007114523001344. Online ahead of print.ABSTRACTSterol regulatory element-binding protein 2 (SREBP2) is considered to be a major regulator to control cholesterol homeostasis in mammals. However, the role of SREBP2 in teleost remains poorly understand. Here, we explored the molecular characterization of SREBP2 and identified SREBP2 as a key modulator for 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) and 7-dehydrocholesterol reductase (DHCR7) which were rate-limiting enzymes of cholesterol biosynthesis. Moreover, dietary palm oil (PO) in vivo or palmitic acid (PA) treatmen...
Source: The British Journal of Nutrition - September 12, 2023 Category: Nutrition Authors: Zengqi Zhao Baolin Li Qiang Chen Xiaojun Xiang Xiang Xu Shangzhe Han Wencong Lai Yueru Li Wei Xu Kangsen Mai Qinghui Ai Source Type: research

Successes and challenges in extracting information from DICOM image databases for audit and research
Br J Radiol. 2023 Sep 12:20230104. doi: 10.1259/bjr.20230104. Online ahead of print.ABSTRACTIn radiography, much valuable associated data (metadata) is generated during image acquisition. The current setup of picture archive and communication systems (PACS) can make extraction of this metadata difficult, especially as it is typically stored with the image. The aim of this work is to examine the current challenges in extracting image metadata and to discuss the potential benefits of using this rich information. This work focuses on breast screening, though the conclusions are applicable to other modalities.The data stored i...
Source: The British Journal of Radiology - September 12, 2023 Category: Radiology Authors: Alistair Mackenzie Emma Lewis John Loveland Source Type: research

AI pitfalls and what not to do: Mitigating bias in AI
We describe these pitfalls by framing them in the larger AI lifecycle from problem definition, dataset selection and curation, model training and deployment emphasizing that bias exists across a spectrum and is a sequela of a combination of both human and machine factors.PMID:37698583 | DOI:10.1259/bjr.20230023
Source: The British Journal of Radiology - September 12, 2023 Category: Radiology Authors: Judy Wawira Gichoya Kaesha Thomas Leo Anthony Celi Nabile Safdar Imon Banerjee John D Banja Laleh Seyyed-Kalantari Hari Trivedi Saptarshi Purkayastha Source Type: research

Artificial intelligence in mental healthcare: a scoping review
Br J Radiol. 2023 Sep 12:20230213. doi: 10.1259/bjr.20230213. Online ahead of print.ABSTRACTArtificial intelligence is disrupting the field of mental healthcare through applications in computational psychiatry, which leverages quantitative techniques to inform our understanding, detection, and treatment of mental illnesses. This paper provides an overview of artificial intelligence technologies in modern mental healthcare and surveys recent advances made by researchers, focusing on the nascent field of digital psychiatry. We also consider the ethical implications of artificial intelligence playing a greater role in mental ...
Source: The British Journal of Radiology - September 12, 2023 Category: Radiology Authors: Kevin W Jin Qiwei Li Yang Xie Guanghua Xiao Source Type: research

AI in medical imaging grand challenges: translation from competition to research benefit and patient care
Br J Radiol. 2023 Sep 12:20221152. doi: 10.1259/bjr.20221152. Online ahead of print.ABSTRACTArtificial intelligence (AI), in one form or another, has been a part of medical imaging for decades. The recent evolution of AI into approaches such as deep learning has dramatically accelerated the application of AI across a wide range of radiologic settings. Despite the promises of AI, developers and users of AI technology must be fully aware of its potential biases and pitfalls, and this knowledge must be incorporated throughout the AI system development pipeline that involves training, validation, and testing. Grand challenges ...
Source: The British Journal of Radiology - September 12, 2023 Category: Radiology Authors: Samuel Armato Karen Drukker Lubomir Hadjiiski Source Type: research

Fatigue recovery and connected factors following paediatric concussion
CONCLUSION: Our findings confirm that fatigue improves during the first 3 months postconcussion and highlights the importance of considering child and parent mental health screening when assessing patients with persisting postconcussive symptoms.PMID:37699656 | DOI:10.1136/bjsports-2023-106894
Source: British Journal of Sports Medicine - September 12, 2023 Category: Sports Medicine Authors: Fabian Fabiano Michael Takagi Nicholas Anderson Franz E Babl Silvia Bressan Cathriona Clarke Katie Davies Gavin A Davis Kevin Dunne Stephen Hearps Vera Ignjatovic Vanessa C Rausa Marc Seal Vicki Anderson Source Type: research

Exploring the pain and disability continuum in adolescents with non-traumatic anterior knee pain: a mediation analysis using individual participant data of prospective studies
CONCLUSION: We found an effect of pain on sports-related disability at 6 months which appears to be independent of lower extremity muscle strength, or depression/anxiety and knee confidence in adolescents with non-traumatic anterior knee pain.PMID:37699655 | DOI:10.1136/bjsports-2023-107177
Source: British Journal of Sports Medicine - September 12, 2023 Category: Sports Medicine Authors: Sinead Holden Hopin Lee Marienke van Middelkoop Adolescent Knee Health Group Michael Skovdal Rathleff adolescent knee health group Source Type: research

Relationship between urinary potassium excretion, serum potassium levels, and cardiac injury in non-dialysis chronic kidney disease: KoreaN cohort study for Outcome in patients With Chronic Kidney Disease (KNOW-CKD)
Br J Nutr. 2023 Sep 11:1-21. doi: 10.1017/S0007114523002064. Online ahead of print.ABSTRACTAlthough the cardiovascular benefits of an increased urinary potassium excretion have been suggested, little is known about the potential cardiac association of urinary potassium excretion in patients with chronic kidney disease (CKD). In addition, whether the cardiac association of urinary potassium excretion was mediated by serum potassium levels has not been studied yet. We reviewed the data of 1,633 patients from a large-scale multicenter prospective Korean study (2011-2016). Spot urinary potassium to creatinine ratio was used as...
Source: The British Journal of Nutrition - September 11, 2023 Category: Nutrition Authors: Hyang Ki Min Su Ah Sung Ji Yong Jung Yun Kyu Oh Kyu Beck Lee Sue K Park Kook-Hwan Oh Curie Ahn Sung Woo Lee Source Type: research

Association of dietary and lifestyle inflammation score with type 2 diabetes mellitus and cardiometabolic risk factors in Iranian adults: Sabzevar Persian Cohort Study
In this study, we identified and recruited 619 patients with T2DM and 2113 without T2DM from 35-75 years old men and women in the baseline phase of the Sabzevar Persian Cohort Study. Using a validated 115-item semi-quantitative food frequency questionnaire, we calculated a 19-component DIS and a 3-component LIS weighted by circulating inflammation biomarkers. The DIS, LIS, and DLIS associations with diabetes were assessed by multivariable logistic regression analysis. Participants had a mean age of 48.29±8.53 (without T2DM: 47.66±8.42; T2DM: 50.44±8.57). Individuals in the highest compared to the lowest tertiles of DLIS...
Source: The British Journal of Nutrition - September 11, 2023 Category: Nutrition Authors: Farnush Bakhshimoghaddam Sima Jafarirad Elham Maraghi Fereshteh Ghorat Source Type: research

Promoting societal resilience during the COVID-19 pandemic: a multi-country analysis of public health strategies
CONCLUSIONS: The COVID-19 pandemic highlighted the importance of Public Health in developing proper strategies and utilizing digitals tools to counteract infodemic and spread relevant information. Healthcare workers should improve their communication skills to face future epidemics and be trusted by the population. Social media and digital platforms should be studied and used effectively in times of emergency.PMID:37695174 | DOI:10.23750/abm.v94iS3.14562
Source: Acta Bio-Medica : Atenei Parmensis - September 11, 2023 Category: General Medicine Authors: Anna Carole D'Amelio Sarah Cataldi Giulia Dallagiacoma Leandro Gentile Anna Odone Carlo Signorelli Source Type: research

Innovative COVID-19 diagnostics and testing strategies in Italy, Denmark, UK, Israel and Sweden: a comparative analysis including tests, incidence and mortality
In this study, we analyzed the use of these techniques in five countries (i.e. Italy, Denmark, the United Kingdom, Sweden, and Israel) based on their specific national testing and contact tracing strategies. We also examined the number of tests performed per week, the positivity rate of tests, and the mortality rate in these populations during the same time periods. These countries were chosen based on the directives of the consortium involved in the CORONADX project.PMID:37695173 | DOI:10.23750/abm.v94iS3.14565
Source: Acta Bio-Medica : Atenei Parmensis - September 11, 2023 Category: General Medicine Authors: Pietro Melodia Manuel Stocchi Leandro Gentile Anna Odone Cristina Renzi Carlo Signorelli Source Type: research

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