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Therapeutic Potential of Bee and Scorpion Venom Phospholipase A2 (PLA2): A Narrative Review
Iran J Med Sci. 2022 Jul;47(4):300-313. doi: 10.30476/IJMS.2021.88511.1927.ABSTRACTVenomous arthropods such as scorpions and bees form one of the important groups with an essential role in medical entomology. Their venom possesses a mixture of diverse compounds, such as peptides, some of which have toxic effects, and enzymatic peptide Phospholipase A2 (PLA2) with a pharmacological potential in the treatment of a wide range of diseases. Bee and scorpion venom PLA2 group III has been used in immunotherapy, the treatment of neurodegenerative and inflammatory diseases. They were assessed for antinociceptive, wound healing, ant...
Source: Cancer Control - August 3, 2022 Category: Cancer & Oncology Authors: Parisa Soltan-Alinejad Hamzeh Alipour Davood Meharabani Kourosh Azizi Source Type: research

Dietary shifts have consequences for the repertoire of allergens produced by the European house dust mite
This study aimed to evaluate the effects of mite‐rearing media on allergen production. Mites were adapted to feed on culture media supplemented with proteins, lipids, carbohydrates or beard shavings, and collected to quantify major allergens (Der p 1 and 2) by immunodetection, transcription of allergen genes by real‐time quantitative polymerase chain reaction, and allergen‐related enzymatic activities. All culture media significantly affected the content of major allergens. Modification of macronutrients in the diet produced minor effects on the transcription of allergen genes, but significantly altered mite allergen...
Source: Medical and Veterinary Entomology - April 21, 2017 Category: Veterinary Research Authors: J. C. VIDAL ‐QUIST, F. ORTEGO, S. ROMBAUTS, P. CASTAÑERA, P. HERNÁNDEZ‐CRESPO Tags: Original Article Source Type: research