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Total 1639 results found since Jan 2013.

Antenatal corticosteroids in specific groups at risk of preterm birth: a systematic review
Conclusions There is a paucity of evidence on ACS for women who have diabetes. ACS therapy may have benefits in women with chorioamnionitis and is probably beneficial in FGR. There is limited direct trial evidence on ACS efficacy in women undergoing planned CS in the late preterm period, though the totality of evidence suggests it is probably beneficial. PROSPERO registration number CRD42021267816.
Source: BMJ Open - September 22, 2023 Category: General Medicine Authors: Saito, K., Nishimura, E., Ota, E., Namba, F., Swa, T., Ramson, J., Lavin, T., Cao, J., Vogel, J. P. Tags: Open access, Paediatrics Source Type: research

Effect of robotic-assisted gait training on gait and motor function in spinal cord injury: a protocol of a systematic review with meta-analysis
Introduction Robotic-assisted gait training (RAGT) has been reported to be effective in rehabilitating patients with spinal cord injury (SCI). However, studies on RAGT showed different results due to a varied number of samples. Thus, summarising studies based on robotic-related factors is critical for the accurate estimation of the effects of RAGT on SCI. This work aims to search for strong evidence showing that using RAGT is effective in treating SCI and analyse the deficiencies of current studies. Methods and analysis The following publication databases were electronically searched in December 2022 without restrictions ...
Source: BMJ Open - September 22, 2023 Category: General Medicine Authors: Wang, L., Peng, J.-l., Chen, A.-l. Tags: Open access, Rehabilitation medicine Source Type: research

Multiple chemical sensitivity scoping review protocol: overview of research and MCS construct
Introduction Multiple chemical sensitivity (MCS) has been characterised by reported adverse responses to environmental exposures of common chemical agents (eg, perfumes, paint, cleaning products and other inhaled or ingested agents) in low doses considered non-toxic for the general population. There is currently no consensus on whether MCS can be established as a distinct disorder. Methods and analysis The scoping review of the literature will be guided by five questions: How is MCS defined and which diagnostic criteria have been proposed? What methods are used to report prevalence and incidence estimates of MCS? What are...
Source: BMJ Open - September 22, 2023 Category: General Medicine Authors: Hempel, S., Danz, M., Robinson, K. A., Bolshakova, M., Rodriguez, J., Mears, A., Pham, C., Yagyu, S., Motala, A., Tolentino, D., Akbari, O., Johnston, J. Tags: Open access, Diagnostics Source Type: research

Measurement and outcomes of co-production in health and social care: a systematic review of empirical studies
Conclusions The lack of common approaches to measuring co-production is more problematic than the plurality of measurements itself. Co-production should be measured from three perspectives: outputs of co-production processes, the experiences of participating in co-production processes and outcomes of co-production. Both self-developed study-specific measures and established measures should be used. The maturity of this research field would benefit from the development and use of reporting guidelines.
Source: BMJ Open - September 22, 2023 Category: General Medicine Authors: Nordin, A., Kjellstrom, S., Robert, G., Masterson, D., Areskoug Josefsson, K. Tags: Open access, Health services research Source Type: research

Safety and efficacy of steerable versus non-steerable sheaths for catheter ablation of atrial fibrillation systematic review and meta-analysis
Conclusions Compared with the use of NSS, the use of SS for RF ablation of AF can effectively reduce the recurrence rate of AF and the occurrence of acute PVs reconnection events. However, there is no advantage in shortening the total RF time, fluoroscopy time, total surgical time and reducing complications.
Source: BMJ Open - September 21, 2023 Category: General Medicine Authors: Jin, X., Zhou, Y., Wu, Y., Xie, M. Tags: Open access, Evidence based practice Source Type: research

Patients experience of using colonoscopy as a diagnostic test after a positive FOBT/FIT: a systematic review of the quantitative literature
Conclusion This review highlighted that patient-reported experiences associated with colonoscopy were generally positive. To improve the colonoscopy experience, bowel screening centres should investigate means to: make bowel preparation more acceptable, make colonoscopy less painful and reduce post-colonoscopy symptoms.
Source: BMJ Open - September 21, 2023 Category: General Medicine Authors: Kayal, G., Kerrison, R., Hirst, Y., von Wagner, C. Tags: Open access, Public health Source Type: research

Prevalence and risk factors of stroke in high-altitude areas: a systematic review and meta-analysis
Conclusions The findings of this study provide insights into the pooled prevalence of stroke in high-altitude areas, highlighting variations based on geographic regions and sampling type. Moreover, age, gender, hypertension and obesity were found to be associated with the occurrence of stroke. PROSPERO registration number CRD42022381541.
Source: BMJ Open - September 21, 2023 Category: General Medicine Authors: Zheng, B., Luo, Y., Li, Y., Gu, G., Jiang, J., Chen, C., Chen, Z., Wang, J. Tags: Open access, Neurology Source Type: research

Physical activity and physical fitness among children and adolescents after the onset of the COVID-19 pandemic in the WHO European Region: a systematic review protocol
Introduction The implementation of COVID-19 pandemic-related restrictions resulted in limitations for physical activity (PA) opportunities, which may have initiated a longer-term behavioural change. The protocol describes the methodology for a planned systematic review that aims to summarise changes in PA and physical fitness (PF) in children and adolescents in the WHO European Region after the onset of the COVID-19 pandemic. Methods and analysis The protocol adheres to the ‘Preferred Reporting Items for Systematic Review and Meta-Analysis for Protocols’ (PRISMA-P) statement. Using a peer-reviewed search strat...
Source: BMJ Open - September 20, 2023 Category: General Medicine Authors: Ludwig-Walz, H., Siemens, W., Heinisch, S., Dannheim, I., Loss, J., Bujard, M. Tags: Open access, Sports and exercise medicine, COVID-19 Source Type: research

Incidence of vasa praevia: a systematic review and meta-analysis
Conclusion The incidence of VP in unselected pregnancies is 1 in 1218 pregnancies. This is higher than is previously reported and can be used as a basis to assess whether screening for this condition should be part of routine clinical practice. Incorporation of strategies to screen for VP in routine clinical practice is likely to prevent 5% of stillbirths. PROSPERO registration number CRD42020125495.
Source: BMJ Open - September 20, 2023 Category: General Medicine Authors: Zhang, W., Giacchino, T., Chanyarungrojn, P. A., Ionescu, O., Akolekar, R. Tags: Open access, Obstetrics & Gynaecology Obstetrics and gynaecology Source Type: research

Exploring experiences of times without care and encounters in dementia: protocol for a living and adaptive evidence map
Introduction Individuals with dementia spend most of the day without care, without encounters, and usually without activity. Although this has been proven in studies, there is a knowledge gap on how individuals with dementia experience these periods of time. Such knowledge would be highly relevant for health professionals and relatives to develop adequate strategies for dealing with these periods of time. The FreiZeit study aims to reconstruct periods of time without care and encounters from the perspective of individuals with dementia and formal and informal carers. The specific objective of this review is to provide a co...
Source: BMJ Open - September 20, 2023 Category: General Medicine Authors: Hirt, J., Adlbrecht, L., Maurer, C., Beer, T. Tags: Open access, Public health Source Type: research

Resilience perspective on healthcare professionals adaptations to changes and challenges resulting from the COVID-19 pandemic: a meta-synthesis
Conclusion Healthcare professionals demonstrated significant adaptive capacity when faced with challenges imposed by the COVID-19 pandemic. Several adaptations were identified as beneficial for future organisational healthcare service changes, while others exposed weaknesses in healthcare system designs and capacity, leading to dysfunctional adaptations. Healthcare professionals’ experiences working during the COVID-19 pandemic present a unique opportunity to learn how healthcare systems rapidly respond to changes, and how resilient healthcare services can be built globally.
Source: BMJ Open - September 20, 2023 Category: General Medicine Authors: Knutsen Glette, M., Ludlow, K., Wiig, S., Bates, D. W., Austin, E. E. Tags: Open access, Health services research, COVID-19 Source Type: research

Transdiagnostic MRI markers of psychopathology following traumatic brain injury: a systematic review and network meta-analysis protocol
Introduction Psychopathology following traumatic brain injury (TBI) is a common and debilitating consequence that is often associated with reduced functional and psychosocial outcomes. There is a lack of evidence regarding the neural underpinnings of psychopathology following TBI, and whether there may be transdiagnostic neural markers that are shared across traditional psychiatric diagnoses. The aim of this systematic review and meta-analysis is to examine the association of MRI-derived markers of brain structure and function with both transdiagnostic and specific psychopathology following moderate–severe TBI. Meth...
Source: BMJ Open - September 19, 2023 Category: General Medicine Authors: Samiotis, A., Hicks, A. J., Ponsford, J., Spitz, G. Tags: Open access, Radiology and imaging Source Type: research

Effects of PCSK9 inhibitors on coronary microcirculation, inflammation and cardiac function in patients with CHD after PCI: a protocol for systematic review and meta-analysis
This study is a systematic review of published literature data and no special ethical approval was required. PROSPERO registration number CRD42022346189.
Source: BMJ Open - September 18, 2023 Category: General Medicine Authors: Ye, X., Wang, S., Liu, X., Wu, Q., Lv, Y., Lv, Q., Li, J., Li, L., Yang, Y. Tags: Open access, Cardiovascular medicine Source Type: research

Prevalence of neck pain and its associated factors in Africa: a systematic review and meta-analysis protocol
Discussion This will be the first systematic review and meta-analysis to systematically identify and synthesise available literature on the prevalence of neck pain and its associated factors in Africa. The results of this review may assist health professionals and policymakers to plan and implement evidence-based strategies that will lessen the burden of neck pain. Ethics and dissemination Data from previously published studies will be collected and analysed and hence ethical approval will not be sought for this study. The results of this review will be disseminated through publication in a peer-reviewed academic journal ...
Source: BMJ Open - September 18, 2023 Category: General Medicine Authors: Mukhtar, N. B., Ibrahim, A. A., Mohammed, J. Tags: Open access, Epidemiology Source Type: research

Protocol for a systematic review and meta-analysis of tobacco-cessation interventions delivered perioperatively
Introduction Tobacco smoking is associated with a substantially increased risk of perioperative complications. The perioperative period is an opportunity to introduce tobacco-cessation strategies. A previous systematic review provided evidence that perioperative interventions increase short-term abstinence and may reduce postoperative complications. The evidence base has since expanded, with the subsequent publication of numerous randomised studies. This protocol outlines a systematic review examining the impact of perioperative tobacco-cessation interventions on successful abstinence from tobacco smoking, and on the incid...
Source: BMJ Open - September 15, 2023 Category: General Medicine Authors: Harrogate, S. R., Barnes, J. D., Gupta, S., Rudd, S., Banerjee, T., Thomas, K., Hinchliffe, R., Mouton, R. Tags: Open access, Anaesthesia Source Type: research