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Total 1639 results found since Jan 2013.

Facilitators of and barriers to buprenorphine initiation for people with opioid use disorder in the emergency department: protocol for a scoping review
Introduction Buprenorphine–naloxone is recommended as a first-line agent for the treatment of opioid use disorder. Although initiation of buprenorphine in the emergency department (ED) is evidence based, barriers to implementation persist. A comprehensive review and critical analysis of both facilitators of and barriers to buprenorphine initiation in ED has yet to be published. Our objectives are (1) to map the implementation of buprenorphine induction pathway literature and synthesise what we know about buprenorphine pathways in EDs and (2) to identify gaps in this literature with respect to barriers and facilitator...
Source: BMJ Open - September 27, 2021 Category: General Medicine Authors: Bozinoff, N., Soobiah, C., Rodak, T., Bucago, C., Kingston, K., Klaiman, M., Poynter, B., Samuels, G., Schoenfeld, E., Shelton, D., Kalocsai, C. Tags: Open access, Addiction Source Type: research

The relative risk of fatal poisoning by methadone or buprenorphine within the wider population of England and Wales
Conclusions Our analysis of the relative safety of buprenorphine and methadone for opioid substitution treatment reveals that buprenorphine is six times safer than methadone with regard to overdose risk among the general population. Clinicians should be aware of the increased risk of prescribing methadone, and tighter regulations are needed to prevent its diversion.
Source: BMJ Open - May 29, 2015 Category: Journals (General) Authors: Marteau, D., McDonald, R., Patel, K. Tags: Open access, Addiction, Evidence based practice, Medical management, Public health Research Source Type: research

Observational study of the safety of buprenorphine+naloxone in pregnancy in a rural and remote population
Conclusions Retrospective data suggest that there likely is no harm from taking buprenorphine+naloxone opioid agonist treatment in pregnancy. Larger, prospective studies are needed to further assess safety.
Source: BMJ Open - October 30, 2016 Category: Journals (General) Authors: Jumah, N. A., Edwards, C., Balfour-Boehm, J., Loewen, K., Dooley, J., Gerber Finn, L., Kelly, L. Tags: Open access, Addiction, Medical management, Paediatrics, Public health, Obgyn Research Source Type: research

Experience and response to a randomised controlled trial of extended-release injectable buprenorphine versus sublingual tablet buprenorphine and oral liquid methadone for opioid use disorder: protocol for a mixed-methods evaluation
This study aims to investigate the experiences of participants who have been offered BUP-XR (evaluation 1), health-related quality-of-life among participants who have opted to receive BUP-XR longer term (evaluation 2) and the experiences of participants allocated to receive BUP-XR or BUP-SL or MET with the offer of adjunctive personalised psychosocial intervention (evaluation 3). Methods and analysis Three qualitative–quantitative (mixed-methods) evaluations embedded in a five-centre, head-to-head, randomised controlled trial of BUP-XR versus BUP-SL and MET in the UK. Evaluation 1 is a four-centre interview anchored...
Source: BMJ Open - October 21, 2022 Category: General Medicine Authors: Lowry, N., Cowden, F., Day, E., Gilvarry, E., Johnstone, S., Murray, R., Kelleher, M., Mitcheson, L., Marsden, J. Tags: Open access, Addiction Source Type: research

158: assessing the quality of search strategies in decision support system (dss) systematic reviews
Conclusions: Lack of duplicate literature searching in systematic reviews was notable. Although most of SRs were searched more than four databases but it seems that in most of them the major databases were not searched and instead, local or specialized databases were considered. Low tendency to grey literature searching was remarkable. It seems that the quality of reporting search strategies in the field of DSS is poor or moderate.
Source: BMJ Open - February 7, 2017 Category: Journals (General) Authors: Fathifar, Z., Hasankandi, H. S., Sadeghi-Ghyassi, F. Tags: Open access Oral Source Type: research

184: key word validity ratio (kwvr); a tool for validity of keywords for building an accurate literature search strategy
Conclusion: KWVR can be used as a valid tool for validating eligible terms for literature search strategy construction especially for systematic reviews and scientometrics studies.
Source: BMJ Open - February 7, 2017 Category: Journals (General) Authors: Gavgani, V. Z., Vahed, N. Tags: Open access Oral Source Type: research

Impact of a health campaign on Chinese public awareness of stroke: evidence from internet search data
Conclusions The WSD campaign increased internet search activity. These research techniques can be applied to evaluation of other health campaigns. Advancing understanding of public demand will enable tailoring of the campaign and strengthen health management.
Source: BMJ Open - December 14, 2021 Category: General Medicine Authors: Cao, M., Guan, T., Han, X., Shen, B., Chao, B., Liu, Y. Tags: Open access, Public health Source Type: research

A search strategy to identify studies on the prognosis of work disability: a diagnostic test framework
Conclusions The Work Disability Prognosis filter will help practitioners and researchers who want to find prognostic evidence in the area of work disability evaluation. However, further refining of this filter is possible and needed, especially for the practitioner for whom efficiency is especially important.
Source: BMJ Open - May 19, 2015 Category: Journals (General) Authors: Kok, R., Verbeek, J. A. H. M., Faber, B., van Dijk, F. J. H., Hoving, J. L. Tags: Open access, Epidemiology, Evidence based practice, Occupational and environmental medicine, Public health Research Source Type: research

What are the factors associated with good mental health among Aboriginal children in urban New South Wales, Australia? Phase I findings from the Study of Environment on Aboriginal Resilience and Child Health (SEARCH)
Conclusions Most children who participated in SEARCH were not at high risk for emotional or behavioural problems. Promising targets for efforts to promote mental health among urban Aboriginal children may include the timely provision of medical care for children and provision of additional support for parents and carers experiencing mental or physical health problems, for adolescent boys and for young people in the foster care system.
Source: BMJ Open - July 4, 2016 Category: Journals (General) Authors: Williamson, A., D'Este, C., Clapham, K., Redman, S., Manton, T., Eades, S., Schuster, L., Raphael, B. Tags: Open access, Mental health, Public health Research Source Type: research

PubMed search filters for the study of putative outdoor air pollution determinants of disease
Conclusions The proposed search filters could help healthcare professionals investigate environmental determinants of medical conditions that could be potentially related to outdoor air pollution.
Source: BMJ Open - December 20, 2016 Category: Journals (General) Authors: Curti, S., Gori, D., Di Gregori, V., Farioli, A., Baldasseroni, A., Fantini, M. P., Christiani, D. C., Violante, F. S., Mattioli, S. Tags: Open access, Epidemiology, Evidence based practice, Occupational and environmental medicine, Public health, Research methods Source Type: research

149: training effective search skills in evidence-based medicine in the clinic in bushehr`s persian gulf martyrs hospital in 2016: a descriptive study
Conclusion: Training students who have recently entered to the clinical stage, for doing effective search on evidence-based medical information in order to meet the needs of the medical community and reduce medical errors that occur in clinical practice, is necessary.
Source: BMJ Open - February 7, 2017 Category: Journals (General) Authors: zareivenovel, M., khosravi, A. Tags: Open access Poster Source Type: research

Sedentary behaviour in non-ambulant children and young people with physical disabilities: a systematic search and review protocol
The objectives of this systematic search and review are to: Identify all peer-reviewed articles relating to sedentary behaviour of non-ambulant children and young people. Categorise the articles according to study design and four subquestions relating to (i) measurement, (ii) patterns, (iii) associated risks and (iv) interventions to reduce sedentary time or behaviour. Critically appraise quality of the articles using established critical appraisal tools. Summarise the evidence for each subquestion. Describe its cumulative strength and identify knowledge gaps. Methods and analysis This protocol was developed using the ...
Source: BMJ Open - December 3, 2021 Category: General Medicine Authors: Bradbury, M., O'Brien, C., Giles, N., Fenton, S., Neilson, S., Duda, J. L. Tags: Open access, Rehabilitation medicine Source Type: research

Online information on face masks: analysis of websites in Italian and English returned by different search engines
Conclusions This study suggests that: (1) public health agencies should increase their web presence in providing correct information on face masks; (2) search engines should improve the information quality criteria in their ranking; (3) the public should be more informed on issues related to the use of masks and disabilities, mental health and stigma arising for those people who cannot wear masks.
Source: BMJ Open - July 8, 2021 Category: General Medicine Authors: Mehta, S., Ghezzi, D., Catalani, A., Vanzolini, T., Ghezzi, P. Tags: Open access, Public health, COVID-19 Source Type: research

Health conditions of migrants, refugees and asylum seekers on search and rescue vessels on the central Mediterranean Sea, 2016-2019: a retrospective analysis
Conclusion The limited testing and diagnostics capacity of the outpatient department, space limitations, stigma and the generally short length of stay of migrants, refugees and asylum seekers on the ships have likely led to an underestimation of morbidities, including mental health conditions and SGBV. The main diagnoses on board were directly related to journey on land and sea and stay in Libya. We conclude that this population may be relatively young and healthy but displays significant journey-related illnesses and includes migrants, refugees and asylum seekers who have suffered significant violence during their transit...
Source: BMJ Open - January 11, 2022 Category: General Medicine Authors: van Boetzelaer, E., Fotso, A., Angelova, I., Huisman, G., Thorson, T., Hadj-Sahraoui, H., Kremer, R., Kuehne, A. Tags: Open access, Epidemiology Source Type: research

Identification of antithrombotic drugs related to total joint replacement using anonymised free-text notes: a search strategy in the Clinical Practice Research Datalink
Conclusions We have developed a useful method to identify additional exposure to NOACs or LMWHs with TJR surgery.
Source: BMJ Open - November 30, 2015 Category: Journals (General) Authors: Nielen, J. T., van den Bemt, B. J. F., Boonen, A., Dagnelie, P. C., Emans, P. J., Veldhorst, N., Lalmohamed, A., van Staa, T.-P., de Vries, F. Tags: Open access, Epidemiology, Pharmacology and therapeutics, Rheumatology, Surgery Research Source Type: research