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Source: Deutsches Arzteblatt International
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Total 860 results found since Jan 2013.
Opioid Rotation in Cancer Pain Treatment.
CONCLUSION: Opioid rotation can improve analgesia and patient satisfaction. The success of opioid rotation appears to depend on the magnitude of the initial dose, among other factors. Tables of equianalgesic doses should be considered no more than a rough guide for determining the dose of the new drug. Rotations to methadone should be carried out under clinical supervision in experienced hands.
PMID: 29563006 [PubMed - in process]
Source: Deutsches Arzteblatt International - March 24, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research
The Efficacy of Body-Oriented Yoga in Mental Disorders.
CONCLUSION: Body-oriented yoga with asanas and pranayama as central components is a promising complementary treatment for mental disorders and should be investigated in further high-quality studies.
PMID: 27118717 [PubMed - in process]
Source: Deutsches Arzteblatt International - April 28, 2016 Category: Journals (General) Tags: Dtsch Arztebl Int Source Type: research
The Opportunities and Limitations of Minimally Invasive Cardiac Surgery.
CONCLUSION: Specialized surgeons and centers can now carry out many cardiac valvular and bypass operations via minithoracotomy rather than sternotomy. According to current evidence, these minimally invasive techniques yield results that are at least as good as classic open-heart surgery.
PMID: 29229038 [PubMed - in process]
Source: Deutsches Arzteblatt International - December 14, 2017 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research
The Role of Microbiota in Preventing Multidrug-Resistant Bacterial Infections.
CONCLUSION: In view of the major problem that multidrug-resistant bacteria pose for the world's population and the resources now being spent on the search for a solution, derived both from public funding and from the pharmaceutical industry, we hope to see new, clinically useful approaches being developed and implemented in the near future.
PMID: 31658936 [PubMed - in process]
Source: Deutsches Arzteblatt International - October 31, 2019 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research
The Diagnosis, Treatment, and Follow-up of Renal Cell Carcinoma.
CONCLUSION: Minimally invasive surgery and new systemic drugs have expanded the therapeutic options for patients with renal cell carcinoma. The search for new predictive and prognostic markers is now in progress.
PMID: 27658472 [PubMed - in process]
Source: Deutsches Arzteblatt International - September 24, 2016 Category: Journals (General) Tags: Dtsch Arztebl Int Source Type: research
Night Work and the Risk of Depression.
CONCLUSION: Although there is evidence that nighttime shift work (at least, in occupations outside the health sector) does increase the risk of depression, this evidence is not strong enough to sustain a general medical recommendation against shift work for employees with depressive conditions. It would seem appropriate to address this question on an individual basis, with strong support from physicians and close attention to the deleterious psychosocial factors associated with shift work.
PMID: 28669378 [PubMed - in process]
Source: Deutsches Arzteblatt International - July 4, 2017 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research
The Investigation of Suspected Fracture-a Comparison of Ultrasound With Conventional Imaging.
CONCLUSION: Strong evidence supports the use of ultrasound imaging for certain indications in the detection of fractures.
PMID: 29202925 [PubMed - in process]
Source: Deutsches Arzteblatt International - December 7, 2017 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research
Hereditary Neuropathies.
CONCLUSION: The molecular diagnosis of neuropathies has become much more successful through the use of NGS. Although causally directed treatment approaches still need to be developed, the correct diagnosis puts an end to the often highly stressful search for a cause and enables determination of the risk of disease in other members of the patient's family.
PMID: 29478438 [PubMed - in process]
Source: Deutsches Arzteblatt International - February 28, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research
Primary Empty Sella Syndrome and the Prevalence of Hormonal Dysregulation.
CONCLUSION: The data on PES as an incidental finding are too sparse to enable any evidence-based recommendation on the potential indications for hormone testing or its nature and extent. We advise basic neuroendocrinological testing (fasting cortisol, free thyroxine [fT4], estradiol or testosterone, insulin-like growth factor 1 [IGF-1], and prolactin). There is an unexplained discrepancy between the reported high prevalence of pituitary insufficiency among persons with PES and its low prevalence in epidemiologic studies. We suspect that the former may be high because of selection bias in the publications that we reviewed, ...
Source: Deutsches Arzteblatt International - March 8, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research
Liquid Biopsy in Tumor Genetic Diagnosis.
CONCLUSION: Liquid biopsy and tumor tissue analysis are complementary, rather than alternative, techniques for therapeutically relevant genetic investigation of tumors. Comparative studies are needed so that further indications can be determined for liquid biopsy in the diagnostic evaluation of cancer.
PMID: 29587961 [PubMed - in process]
Source: Deutsches Arzteblatt International - March 30, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research
Domestic Violence Against Men-Prevalence and Risk Factors.
CONCLUSION: The prevalence of violence against men and the risk factors for it have been little studied to date. It would be desirable for preventive measures to be further developed and for special help to be made available to the affected men.
PMID: 33087241 [PubMed - in process]
Source: Deutsches Arzteblatt International - October 23, 2020 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research
Raynaud's Phenomenon: A Vascular Acrosyndrome That Requires Long-Term Care
CONCLUSION: At onset or after years of latency, patients with Raynaud phenomenon may have an underlying disease (most commonly a connective tissue disease). Long-term specialist care is necessary for asymptomatic patients with risk factors and for those with clinically manifest symptoms of an underlying condition alike.PMID:33632387 | DOI:10.3238/arztebl.m2021.0023
Source: Deutsches Arzteblatt International - February 26, 2021 Category: General Medicine Authors: Peter Klein-Weigel Oliver Sander Simone Reinhold Jessica Nielitz Julia Steindl Jutta Richter Source Type: research
Breast Reconstruction Following Cancer Treatment.
CONCLUSION: No randomized controlled trials have yet been conducted to compare the reconstructive techniques with each other. If radiotherapy will not be performed, immediate reconstruction with an implant is recommended. On the other hand, if post-mastectomy radiotherapy is indicated, then secondary autol ogous breast reconstruction is the procedure of choice. Future studies should address patients' quality of life and the long-term aesthetic results after breast reconstruction.
PMID: 26377531 [PubMed - in process]
Source: Deutsches Arzteblatt International - September 18, 2015 Category: Journals (General) Tags: Dtsch Arztebl Int Source Type: research
The Effects of Climate Change on Patients With Chronic Lung Disease.
CONCLUSION: Heat waves significantly increase morbidity and mortality in patients with chronic lung disease. The argument that the excess mortality during heat waves is compensated for by a decrease in mortality in the subsequent weeks/months (mortality displacement) should not be used as an excuse for delay in implementing adaptive strategies to protect lung patients from this risk to their health.
PMID: 26900154 [PubMed - in process]
Source: Deutsches Arzteblatt International - February 24, 2016 Category: Journals (General) Tags: Dtsch Arztebl Int Source Type: research
Task-Specific Dystonia in Professional Musicians.
CONCLUSION: The Bradford Hill causality criteria indicate that intensive playing is related to the development of musician's dystonia. In particular, the association of the type of instrument with the site of dystonia supports this thesis. The indings imply that task-specific dystonia in professional musicians should be included in the list of occupational diseases in Germany.
PMID: 26900153 [PubMed - in process]
Source: Deutsches Arzteblatt International - February 24, 2016 Category: Journals (General) Tags: Dtsch Arztebl Int Source Type: research
