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Primary vaccination in adult patients after allogeneic hematopoietic stem cell transplantation - A single center retrospective efficacy analysis
Vaccine. 2021 May 25:S0264-410X(21)00511-9. doi: 10.1016/j.vaccine.2021.04.052. Online ahead of print.ABSTRACTAllogeneic hematopoietic stem cell transplantation (alloHSCT) results in a loss of humoral immunity and subsequent risk for severe infections. Thus, re-vaccination is required but may fail due to incomplete immune reconstitution. We retrospectively analyzed predictors of immune response to primary vaccination applied according to the EBMT (European Blood and Marrow Transplantation Group) recommendations. Serologic response to vaccination against diphtheria (D), tetanus (T), Bordetella pertussis (aP) and Haemophilus...
Source: Vaccine - May 29, 2021 Category: Allergy & Immunology Authors: Clara Sattler Petra Hoffmann Philipp Yorck Herzberg Daniela Weber Barbara Holler Ute Fehn Annelie Plentz Philipp Beckhove Julia Winkler Matthias Edinger Wolfgang Herr Ernst Holler Daniel Wolff Source Type: research

Fight Aging! Newsletter, August 24th 2020
We report that electrical stimulation (ES) stimulation of post-stroke aged rats led to an improved functional recovery of spatial long-term memory (T-maze), but not on the rotating pole or the inclined plane, both tests requiring complex sensorimotor skills. Surprisingly, ES had a detrimental effect on the asymmetric sensorimotor deficit. Histologically, there was a robust increase in the number of doublecortin-positive cells in the dentate gyrus and SVZ of the infarcted hemisphere and the presence of a considerable number of neurons expressing tubulin beta III in the infarcted area. Among the genes that were unique...
Source: Fight Aging! - August 23, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Best of Highlight HEALTH 2012 – The Year in Review
As the year draws to a close, it’s become a tradition for us to take a look back at the top stories readers were interested in (this month, Highlight HEALTH celebrated it’s sixth year promoting advances in biomedical research). As we have in previous years, we’ve compiled two top ten lists of the most-viewed stories for 2012, one as measured by the absolute number of page views and the other as measured by the average number of page views per day posted. To get a sense of underlying themes for the top ten lists, here’s a tag cloud of terms taken from articles that made the cut: biomarker BMI brain can...
Source: Highlight HEALTH - January 1, 2013 Category: Medical Scientists Authors: Walter Jessen, Ph.D. Source Type: blogs