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Emerging pharmacological strategies for treating and preventing mpox
Expert Rev Clin Pharmacol. 2023 Aug 17. doi: 10.1080/17512433.2023.2249820. Online ahead of print.ABSTRACTINTRODUCTION: Since May 2022, there have been nearly 87,000 documented cases of mpox worldwide, with 119 deaths. Pharmacological interventions for mpox include the MVA-BN smallpox vaccine, tecovirimat, cidofovir or its pro-drug brincidofovir, and vaccinia immune globulin intravenous (VIGIV).AREAS COVERED: The literature search and information gathering for this review included the PubMed database focusing on mpox and monkeypox, in combination with tecovirimat, brincidofovir, cidofovir, VIGIV, and smallpox vaccine. WHO....
Source: Pharmacological Reviews - August 18, 2023 Category: Drugs & Pharmacology Authors: Douglas W Grosenbach Andrew T Russo Emily D Blum Dennis E Hruby Source Type: research

The 2022 human monkeypox outbreak: Clinical review and management guidance
CONCLUSION: There are no FDA-approved treatments for monkeypox infection. Surveillance and detection of monkeypox among high-risk populations should be implemented to help understand the epidemiology of this disease.PMID:36259674 | DOI:10.1093/ajhp/zxac300
Source: American Journal of Health-System Pharmacy : AJHP - October 19, 2022 Category: Drugs & Pharmacology Authors: Mohammed Aldhaeefi Dhakrit Rungkitwattanakul Jacqueise Unonu Careen-Joan Franklin Jessica Lyons Katherine Hager Monika N Daftary Source Type: research

Monkeypox: Virology, Pathophysiology, Clinical Characteristics, Epidemiology, Vaccines, Diagnosis, and Treatments
J Pharm Pharm Sci. 2022;25:297-322. doi: 10.18433/jpps33138.ABSTRACTThe World Health Organization, has declared the recent multiregional outbreak of monkeypox, a global public health emergency. Monkeypox is a zoonotic viral infection endemic to the west and central Africa. It belongs to the Poxviridae family, the Chordopoxvirinae subfamily, and the Orthopoxvirus genus. The Poxviridae family generally consists of complex, large, enveloped, and linear double-stranded DNA viruses. The initial clinical symptoms of monkeypox are often fever, severe headache, lymphadenopathy, myalgia, and fatigue. The skin lesions typically erup...
Source: J Pharm Pharm Sci - September 21, 2022 Category: Drugs & Pharmacology Authors: Marzieh Soheili Sherko Nasseri Maryam Afraie Sorour Khateri Yousef Moradi Seyede Maryam Mahdavi Mortazavi Hamed Gilzad-Kohan Source Type: research

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