MASLD Plus HIV Ups Risk for CVD But Not Liver Disease MASLD Plus HIV Ups Risk for CVD But Not Liver Disease
A large study reveals an increased risk for adverse cardiovascular events but not for liver disease progression in adults with MASLD disease and HIV infection.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 26, 2024 Category: Consumer Health News Tags: Gastroenterology Clinical Summary Source Type: news

Gilead posts quarterly loss, revenue rises 5%
Gilead Sciences reported a first-quarter loss on Thursday after taking a $3.9 billion charge for its recent acquisition of liver drug developer CymaBay Therapeutics, while revenue rose 5% on higher HIV, oncology and liver disease treatment sales. For full-year 2024, Gilead said it still expects…#gileadsciences #cymabaytherapeutics #gilead #cymabay #immunomedics #danieloday (Source: Reuters: Health)
Source: Reuters: Health - April 25, 2024 Category: Consumer Health News Source Type: news

Deep-learning algorithm improves liver fibrosis diagnosis
An algorithm combining the Fibrosis-4 Index (FIB-4) and an ultrasound deep-learning model could improve diagnostic accuracy and referral management for all-cause advanced liver fibrosis, a study published April 23 in Radiology found. Researchers led by Li-Da Chen, PhD, from the First Affiliated Hospital of Sun Yat-sen University in Guangzhou, China found that their combined sequential algorithm improved specificity by over 20% for predicting pathologically advanced liver fibrosis compared with the Fibrosis-4 Index (FIB-4) alone. Additionally, the algorithm reduced unnecessary referrals by 42% without requiring access to l...
Source: AuntMinnie.com Headlines - April 23, 2024 Category: Radiology Authors: Amerigo Allegretto Tags: Ultrasound Artificial Intelligence Source Type: news

Top Pharmaceutical Company evaluates Optimer for precision liver medicine
Optimer delivery vehicle has been shipped to a pharma partner for external evaluation. The specific delivery vehicle could generate new precision therapies for liver disease (Source: The Scientist)
Source: The Scientist - April 22, 2024 Category: Science Tags: The Scientist The Marketplace Source Type: news

UK biotech signs $1bn deal to develop liver disease drugs
Ochre Bio partnering with Germany’s Boehringer Ingelheim on treatments that will harness the organ’s capacity to regenerate (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - April 22, 2024 Category: Pharmaceuticals Source Type: news

MR elastography effective for assessing liver stiffness in children
MR elastography (MRE) is an effective technique for noninvasive monitoring of liver stiffness -- a surrogate for fibrosis -- in children and young adults with autoimmune liver disease, researchers have reported. A team led by first author Jonathan Dillman, MD, of Cincinnati Children’s Hospital Center in Ohio found that MRE liver stiffness measurements were elevated in children and young adults with autoimmune liver disease. The results were published April 18 in the American Journal of Roentgenology. “[As well, these measurements] were not significantly different between subsets of patients with primary sclerosing ch...
Source: AuntMinnie.com Headlines - April 19, 2024 Category: Radiology Authors: Kate Madden Yee Tags: MRI Pediatric Radiology Source Type: news

Heart-Liver Surgery May Help Patients Excluded from Transplant List
Patients with both heart and liver diseases are usually turned away from organ transplant lists. A new dual procedure aims to give them another chance. (Source: WebMD Health)
Source: WebMD Health - April 19, 2024 Category: Consumer Health News Source Type: news

Midlife Deaths of Despair Increased From 1999 to 2022
THURSDAY, April 11, 2024 -- Midlife deaths from suicide, drug overdose, and alcoholic liver disease, collectively known as deaths of despair, increased from 1999 through 2022, according to a research letter published online April 10 in JAMA... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 11, 2024 Category: Pharmaceuticals Source Type: news

CEUS adds to locoregional therapy for liver disease
Contrast-enhanced ultrasound (CEUS) can improve locoregional therapy for treating metastatic disease of the liver, according to early study results presented April 10 at UltraCon. In her presentation, PhD candidate Corinne Wessner from Thomas Jefferson University in Philadelphia, PA, highlighted initial findings from her team’s ongoing work suggesting that microbubble destruction from CEUS triggering is safe and well-tolerated among patients with intrahepatic cholangiocarcinoma (ICC) and metastatic liver disease who also receive transarterial radioembolization with yttrium-90 (Y90-TARE). “When we add the ultrasound-t...
Source: AuntMinnie.com Headlines - April 11, 2024 Category: Radiology Authors: Amerigo Allegretto Tags: Ultrasound Source Type: news

Black and Native Americans Hit Hardest by'Deaths of Despair '
WEDNESDAY, April 10, 2024 -- More middle-aged Black and Native Americans are now falling prey to“deaths of despair” than whites, a new study finds. These deaths -- from suicide, drug overdose and alcoholic liver disease -- initially... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - April 10, 2024 Category: General Medicine Source Type: news

Can Altimmune get its GLP-1 Drug to Market Before Cash Rush Out?
Altimmune Inc. NASDAQ: ALT is a clinical-stage biotechnology company specializing in treating liver disease and obesity. Their lead drug, Pemvidutide, has garnered much attention as a GLP-1/glucagon dual agonist similar to the weight-loss treatments Mounjaro and Zepbound by Eli Lilly and Co. NYSE:…#altimmuneinc #alt #pemvidutide #glp1 #mounjaro #elilillyandco #lly #ozempicandwegovy #novonordiskasnyse #nvo (Source: Reuters: Health)
Source: Reuters: Health - April 9, 2024 Category: Consumer Health News Source Type: news

Is there a safe alcohol consumption limit for the general population and in patients with liver disease? - Romero-G ómez M, Arab JP, Oliveira CP, Hernandez M, Arrese M, Cortez-Pinto H, Bataller R.
Excessive alcohol consumption represents an important burden for health systems worldwide and is a major cause of liver- and cancer-related deaths. Alcohol consumption is mostly assessed by self-report that often underestimates the amount of drinking. Whil... (Source: SafetyLit)
Source: SafetyLit - April 8, 2024 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Scientists Find New Genetic Variants for Obesity
Researchers believe they have discovered a new biological mechanism for obesity, pointing to rare variants on two genes that dramatically increase the risk of carrying excess weight. Research published in the journal Nature Genetics on Thursday points to variants that raise the chance of being obese by as much as six times. Unlike other known variants that affect weight gain in children, these only appear to play a role in adults. [time-brightcove not-tgx=”true”] Unraveling obesity’s mechanisms could help scientists develop new drugs, or tailor existing ones, for a condition that now affects ...
Source: TIME: Health - April 4, 2024 Category: Consumer Health News Authors: Ashleigh Furlong/Bloomberg Tags: Uncategorized healthscienceclimate wire Source Type: news

Scientists find new 'fat genes' that make you six times more likely to be obese - and up to 10,000 Brits carry them
Researchers at the University of Cambridge also found the genetic quirk was linked with an increased risk of non-alcoholic fatty liver disease and of type 2 diabetes. (Source: the Mail online | Health)
Source: the Mail online | Health - April 4, 2024 Category: Consumer Health News Source Type: news

Opinion: A deadly but curable disease is thriving in L.A.'s jails. That's unacceptable
The Los Angeles County jail system needs a concerted effort to screen for and treat the blood-borne liver disease, which kills about 14,000 Americans a year. (Source: L.A. Times - Health)
Source: L.A. Times - Health - April 2, 2024 Category: Consumer Health News Authors: Mark Bunin Benor Source Type: news