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Procedure: Gastroschisis Repair

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Total 83865 results found since Jan 2013.

SCCM Pod-275 44th Critical Care Congress: Is Repair After AKI Linked to Long-Term Outcomes?
Todd Fraser, MD, speaks with John Kellum, MD, MCCM, Professor of Critical Care Medicine at the University of Pittsburgh.
Source: SCCM PodCast - iCritical Care - May 19, 2015 Category: Intensive Care Authors: The Society of Critical Care Medicine (SCCM) Tags: Medicine Source Type: podcasts

Spillover of Early Extubation Practices From the Pediatric Heart Network Collaborative Learning Study*
Conclusions: We observed spillover of extubation practices promoted by the Collaborative Learning Study clinical practice guideline to lower complexity operations not included in the original study that was sustainable 1 year after study completion, though this effect differed across sites and operation subtypes. No changes in postoperative extubation outcomes following higher complexity surgeries were seen. The significant variation in outcomes by site suggests that center-specific factors may have influenced spillover of clinical practice guideline practices.
Source: Pediatric Critical Care Medicine - February 1, 2021 Category: Pediatrics Tags: Cardiac Intensive Care Source Type: research

Systemic Inflammation Increases Energy Expenditure Following Pediatric Cardiopulmonary Bypass
Objectives: To examine the association between cardiopulmonary bypass–related systemic inflammation and resting energy expenditure in pediatric subjects following cardiac surgery. Design: Single-center, prospective cohort study. Setting: Pediatric cardiac critical care unit in Toronto, Canada. Patients: Children with congenital heart disease undergoing cardiopulmonary bypass surgery. Interventions: Resting energy expenditure was determined by indirect calorimetry and the modified Weir equation, using VO2 and VCO2 measured by in-line respiratory mass spectrometry. Measurements were taken at baseline and 6-hour intervals f...
Source: Pediatric Critical Care Medicine - May 1, 2015 Category: Pediatrics Tags: Cardiac Intensive Care Source Type: research

Cellular Immunotherapy for Septic Shock (CISS): A Phase I Clinical Trial.
CONCLUSIONS: The infusion of freshly cultured allogenic bone marrow derived MSCs into participants with septic shock up to a dose of 3 million cells per kg (250 million cells) appears safe. Clinical trial registration available at www.clinicaltrials.gov, ID NCT02421484. PMID: 28960096 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - September 29, 2017 Category: Respiratory Medicine Authors: McIntyre LA, Stewart DJ, Mei SHJ, Courtman D, Watpool I, Granton J, Marshall J, Dos Santos C, Walley KR, Winston BW, Schlosser K, Fergusson DA, Canadian Critical Care Trials Group and the Canadian Critical Care Translational Biology Group Tags: Am J Respir Crit Care Med Source Type: research

Characteristics and Outcomes of Pediatric Patients Supported With Ventricular Assist Device—A Multi-Institutional Analysis*
Conclusions: The pediatric ventricular assist device experience continues to grow, with a significant increase in the number of patients undergoing ventricular assist device implantation and a higher proportion being discharged from hospital on ventricular assist device support in recent years. Underlying congenital heart disease, renal failure, sepsis, cerebrovascular accident, and extracorporeal membrane oxygenation are significantly associated with hospital mortality.
Source: Pediatric Critical Care Medicine - August 1, 2019 Category: Pediatrics Tags: Cardiac Intensive Care Source Type: research

Longer RBC Storage Duration Is Associated With Increased Postoperative Infections in Pediatric Cardiac Surgery
Discussion: Longer RBC storage duration was associated with increased postoperative nosocomial infections. This association may be secondary in part, to the large doses of stored RBCs transfused, from single-donor units. Washing the oldest RBCs was associated with increased morbidity, possibly from increased destruction of older, more fragile erythrocytes incurred by washing procedures. Additional studies examining the effect of RBC storage age on postoperative infection rate in pediatric cardiac surgery are warranted.
Source: Pediatric Critical Care Medicine - March 1, 2015 Category: Pediatrics Tags: Cardiac Intensive Care Source Type: research

Changes in Anesthetic and Postoperative Sedation–Analgesia Practice Associated With Early Extubation Following Infant Cardiac Surgery: Experience From the Pediatric Heart Network Collaborative Learning Study*
Objectives: The Pediatric Heart Network sponsored the multicenter Collaborative Learning Study that implemented a clinical practice guideline to facilitate early extubation in infants after repair of isolated coarctation of the aorta and tetralogy of Fallot. We sought to compare the anesthetic practice in the operating room and sedation-analgesia management in the ICU before and after the implementation of the guideline that resulted in early extubation. Design: Secondary analysis of data from a multicenter study from January 2013 to April 2015. Predefined variables of anesthetic, sedative, and analgesia exposure were...
Source: Pediatric Critical Care Medicine - October 1, 2019 Category: Pediatrics Tags: Cardiac Intensive Care Source Type: research

Improved Risk Stratification in Pediatric Septic Shock Using Both Protein and mRNA Biomarkers: PERSEVERE-XP.
CONCLUSIONS: PERSEVERE-XP combines protein and mRNA biomarkers to provide mortality risk stratification with possible clinical utility. PERSEVERE-XP significantly improves upon PERSEVERE and suggests a role for TP53-related cellular division, repair, and metabolism in the pathophysiology of septic shock. PMID: 28324661 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - March 21, 2017 Category: Respiratory Medicine Authors: Wong HR, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Checchia PA, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Grunwell JR, Lindsell CJ Tags: Am J Respir Crit Care Med Source Type: research

Critical Care Compendium update
LITFL’s Critical Care Compendium is a comprehensive collection of pages concisely covering the core topics and controversies of critical care. Currently there are almost 1,500 entries with more in the works… Some pages are more developed than others, and all the pages are being constantly revised and improved. Links to new references and online resources are added daily, with an emphasis on those that are free and open access (FOAM!). These pages originated from the FCICM exam study notes created by Dr Jeremy Fernando in 2011, and have been updated, modified and added to since. As such will be particularly us...
Source: Life in the Fast Lane - November 17, 2013 Category: Emergency Medicine Doctors Authors: Chris Nickson Tags: Critical Care Compendium Education eLearning Emergency Medicine Featured CCC LITFL collection Source Type: blogs

Utilizing a Collaborative Learning Model to Promote Early Extubation Following Infant Heart Surgery*
Objective: To determine whether a collaborative learning strategy-derived clinical practice guideline can reduce the duration of endotracheal intubation following infant heart surgery. Design: Prospective and retrospective data collected from the Pediatric Heart Network in the 12 months pre- and post-clinical practice guideline implementation at the four sites participating in the collaborative (active sites) compared with data from five Pediatric Heart Network centers not participating in collaborative learning (control sites). Setting: Ten children’s hospitals. Patients: Data were collected for infants following two...
Source: Pediatric Critical Care Medicine - October 1, 2016 Category: Pediatrics Tags: Cardiac Intensive Care Source Type: research

Cardiac Surgery–Associated Kidney Injury in Children and Renal Oximetry
Conclusions: Findings demonstrate that preoperative oxygen supply/demand balance is an important predictor of cardiac surgery–associated acute kidney injury, suggesting lower preoperative (and intraoperative) renal blood flow may be protective. There is not yet a definite link between remote ischemic preconditioning and prevention of cardiac surgery–associated acute kidney injury; however, renal protective effects of sublethal ischemia should continue to be explored.
Source: Pediatric Critical Care Medicine - September 1, 2018 Category: Pediatrics Tags: Cardiac Intensive Care Source Type: research

Acetazolamide Therapy for Metabolic Alkalosis in Critically Ill Pediatric Patients
The objective of this study was to assess the change in 18 hours after initiation of acetazolamide therapy. Design: Retrospective study. Setting: PICU of an urban, tertiary-care children’s hospital. Patients: Mechanically ventilated children (≤ 17 yr) with metabolic alkalosis (pHco–3 ≥ 35 mmol/L). Interventions: None. Measurements and Main Results: Of 153 consecutively screened patients, 61 patients (29 female patients) were enrolled: 18 cardiac patients (after congenital heart disease repair) and 43 noncardiac patients. The cardiac patients were younger than the noncardiac patients (median [interquartile range] ag...
Source: Pediatric Critical Care Medicine - February 1, 2015 Category: Pediatrics Tags: Online Clinical Investigations Source Type: research

Avoiding Furosemide Ototoxicity Associated With Single-Ventricle Repair in Young Infants*
Conclusions: A practice change to ensure slow IV administration of furosemide eliminated permanent hearing loss. Centers caring for critically ill infants, particularly those with single-ventricle anatomy or hypoxia, should review their drug administration guidelines and adhere to best practice for administration of IV furosemide.
Source: Pediatric Critical Care Medicine - April 1, 2019 Category: Pediatrics Tags: Cardiac Intensive Care Source Type: research