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Total 25 results found since Jan 2013.

Sustained Clinical Response of Acquired Epidermodysplasia Verruciformis to Human Papillomavirus Vaccination in a Kidney Transplant Recipient
Actas Dermosifiliogr. 2023 Sep 11:S0001-7310(23)00729-9. doi: 10.1016/j.ad.2023.08.009. Online ahead of print.NO ABSTRACTPMID:37704170 | DOI:10.1016/j.ad.2023.08.009
Source: Actas Dermo-Sifiliograficas - September 13, 2023 Category: Dermatology Authors: M Martinez-Molina M Munera-Campos A Quer J M Carrascosa Source Type: research

A multivalent polyomavirus vaccine elicits durable neutralizing antibody responses in macaques
In this study, we demonstrate that VLPs representing BKPyV genotypes I, II, and IV, as well as JCPyV genotype 2 produced in insect cells elicit robust antibody titers. In rhesus macaques, all monkeys developed neutralizing antibody titers above a previously proposed protective threshold of 10,000. A second inoculation, administered 19 weeks after priming, boosted titers to a plateau of ≥ 25,000 that was maintained for almost two years. No vaccine-related adverse events were observed in any macaques. A multivalent BK/JC VLP immunogen did not show inferiority compared to the single-genotype VLP immunogens. Considering thes...
Source: Vaccine - February 10, 2023 Category: Allergy & Immunology Authors: Alberto Peretti Diana G Scorpio Wing-Pui Kong Yuk-Ying S Pang Michael P McCarthy Kuishu Ren Moriah Jackson Barney S Graham Christopher B Buck Patrick M McTamney Diana V Pastrana Source Type: research

End-Stage Renal Disease: Medical Management
Am Fam Physician. 2021 Nov 1;104(5):493-499.ABSTRACTEnd-stage renal disease (ESRD) is diagnosed when kidney function is no longer adequate for long-term survival without kidney transplantation or dialysis. Primary care clinicians should refer people at risk of ESRD to nephrology to optimize disease management. Kidney transplantation typically yields the best patient outcomes, although most patients are treated with dialysis. The decision to initiate dialysis is best made through shared decision-making. Because most patients with ESRD elect to receive hemodialysis, the preservation of peripheral veins is important for those...
Source: American Family Physician - November 16, 2021 Category: Primary Care Authors: Noah Wouk Source Type: research