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Specialty: Transplant Surgery
Procedure: Transplants
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Total 10419 results found since Jan 2013.
Durable complete response to early immunotherapy discontinuation in a kidney transplant recipient with advanced cutaneous squamous cell carcinoma: A case report and review of literature
CONCLUSION: Organ transplant recipients with complete response to immunotherapy for cutaneous squamous cell carcinoma may continue to respond despite early treatment cessation. This may reduce the risks of late immune-related adverse events and acute graft rejection.PMID:37734447 | DOI:10.1016/j.trim.2023.101932
Source: Transplant Immunology - September 21, 2023 Category: Transplant Surgery Authors: Ziyao Lu Mohammed Afzal Keisuke Shirai Source Type: research
Pain management for liver transplant recipients
We present current evidence-based literature that reviews optimal pain management strategies for this challenging patient demographic.RECENT FINDINGS: Multiple studies have shown that thoracic epidurals provide superior pain control in open hepatic resections. Recent data suggests thoracic epidurals may be safely considered in select liver transplant recipients with normal preoperative coagulation status; however, this evidence is limited, and further studies are needed. When the risks of coagulopathy prohibit epidural placement, truncal blocks such as transversus abdominis plane blocks or quadratus lumborum blocks and abd...
Source: Current Opinion in Organ Transplantation - September 20, 2023 Category: Transplant Surgery Authors: Simrat Kaur Patrick Henthorn Adrian Hendrickse Source Type: research
Coagulation management during liver transplantation: monitoring and decision making for hemostatic interventions
Curr Opin Organ Transplant. 2023 Sep 19. doi: 10.1097/MOT.0000000000001101. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Rebalanced hemostasis describes the precarious balance of procoagulant and antithrombotic proteins in patients with severe liver failure. This review is aimed to discuss currently available coagulation monitoring tests and pertinent decision-making process for plasma coagulation factor replacements during liver transplantation (LT).RECENT FINDINGS: Contemporary viscoelastic coagulation monitoring systems have demonstrated advantages over conventional coagulation tests in assessing the patient's coagu...
Source: Current Opinion in Organ Transplantation - September 20, 2023 Category: Transplant Surgery Authors: Kofi B Vandyck Walter Rusin Samhati Mondal Kenichi A Tanaka Source Type: research
Low-MFI (median fluorescence intensity) pre-transplant DSA (donor specific antibodies) leading to anamnestic antibody mediated rejection in live-related donor kidney transplantation
We present two cases of live-related donor kidney transplants (LDKTs) with low-MFI pre-transplant DSA values who experienced an early acute antibody-mediated rejection (ABMR) as a result of an anamnestic antibody response by DSA against HLA class II antibodies. These results were confirmed by retesting of both pre-transplant and post-transplant archived sera from patients as well as freshly obtained donor cells. Our examples indicate a possible ABMR in patients with low MFI pre-transplant DSA. Reclassification of low vs. high-risk may be appropriate for some patients with low-MFI DSA."PMID:37730185 | DOI:10.1016/j.trim.2023.101931
Source: Transplant Immunology - September 20, 2023 Category: Transplant Surgery Authors: Rajni Chauhan Aseem Kumar Tiwari Geet Aggarwal L Gowri Suresh Mohit Kumar Shyam Bihari Bansal Source Type: research
Bioequivalence evaluation and blood concentration estimation of generic and branded tacrolimus in healthy subjects under fasting: A randomized, four-periods, two-sequences, complete repeated, crossover study
CONCLUSION: Generic tacrolimus (Ruibeirong®) is bioequivalent to branded tacrolimus (Astagraf XL®) with tolerable safety, which AUC predictive equations work well and are interchangeable between the two products.PMID:37730184 | DOI:10.1016/j.trim.2023.101933
Source: Transplant Immunology - September 20, 2023 Category: Transplant Surgery Authors: Yulin Niu Gongbin Lan Jina Wang Tianzhong Yan Peng Jin Source Type: research
Association between blood transfusion after kidney transplantation and risk for the development of de novo HLA donor-specific antibodies and poor clinical outcomes: A single-center retrospective study
CONCLUSIONS: Our study showed that blood transfusion after transplantation is associated with the occurrence of de novo DSAs increasing an immunological risk for poor clinical outcomes for kidney transplantation recipients.PMID:37730183 | DOI:10.1016/j.trim.2023.101930
Source: Transplant Immunology - September 20, 2023 Category: Transplant Surgery Authors: Zhong-Yu Kang Chun Liu Wei Liu Daihong Li Source Type: research
Pain management for liver transplant recipients
We present current evidence-based literature that reviews optimal pain management strategies for this challenging patient demographic.RECENT FINDINGS: Multiple studies have shown that thoracic epidurals provide superior pain control in open hepatic resections. Recent data suggests thoracic epidurals may be safely considered in select liver transplant recipients with normal preoperative coagulation status; however, this evidence is limited, and further studies are needed. When the risks of coagulopathy prohibit epidural placement, truncal blocks such as transversus abdominis plane blocks or quadratus lumborum blocks and abd...
Source: Current Opinion in Organ Transplantation - September 20, 2023 Category: Transplant Surgery Authors: Simrat Kaur Patrick Henthorn Adrian Hendrickse Source Type: research
Coagulation management during liver transplantation: monitoring and decision making for hemostatic interventions
Curr Opin Organ Transplant. 2023 Sep 19. doi: 10.1097/MOT.0000000000001101. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Rebalanced hemostasis describes the precarious balance of procoagulant and antithrombotic proteins in patients with severe liver failure. This review is aimed to discuss currently available coagulation monitoring tests and pertinent decision-making process for plasma coagulation factor replacements during liver transplantation (LT).RECENT FINDINGS: Contemporary viscoelastic coagulation monitoring systems have demonstrated advantages over conventional coagulation tests in assessing the patient's coagu...
Source: Current Opinion in Organ Transplantation - September 20, 2023 Category: Transplant Surgery Authors: Kofi B Vandyck Walter Rusin Samhati Mondal Kenichi A Tanaka Source Type: research
Low-MFI (median fluorescence intensity) pre-transplant DSA (donor specific antibodies) leading to anamnestic antibody mediated rejection in live-related donor kidney transplantation
We present two cases of live-related donor kidney transplants (LDKTs) with low-MFI pre-transplant DSA values who experienced an early acute antibody-mediated rejection (ABMR) as a result of an anamnestic antibody response by DSA against HLA class II antibodies. These results were confirmed by retesting of both pre-transplant and post-transplant archived sera from patients as well as freshly obtained donor cells. Our examples indicate a possible ABMR in patients with low MFI pre-transplant DSA. Reclassification of low vs. high-risk may be appropriate for some patients with low-MFI DSA."PMID:37730185 | DOI:10.1016/j.trim.2023.101931
Source: Transplant Immunology - September 20, 2023 Category: Transplant Surgery Authors: Rajni Chauhan Aseem Kumar Tiwari Geet Aggarwal L Gowri Suresh Mohit Kumar Shyam Bihari Bansal Source Type: research
Bioequivalence evaluation and blood concentration estimation of generic and branded tacrolimus in healthy subjects under fasting: A randomized, four-periods, two-sequences, complete repeated, crossover study
CONCLUSION: Generic tacrolimus (Ruibeirong®) is bioequivalent to branded tacrolimus (Astagraf XL®) with tolerable safety, which AUC predictive equations work well and are interchangeable between the two products.PMID:37730184 | DOI:10.1016/j.trim.2023.101933
Source: Transplant Immunology - September 20, 2023 Category: Transplant Surgery Authors: Yulin Niu Gongbin Lan Jina Wang Tianzhong Yan Peng Jin Source Type: research
Association between blood transfusion after kidney transplantation and risk for the development of de novo HLA donor-specific antibodies and poor clinical outcomes: A single-center retrospective study
CONCLUSIONS: Our study showed that blood transfusion after transplantation is associated with the occurrence of de novo DSAs increasing an immunological risk for poor clinical outcomes for kidney transplantation recipients.PMID:37730183 | DOI:10.1016/j.trim.2023.101930
Source: Transplant Immunology - September 20, 2023 Category: Transplant Surgery Authors: Zhong-Yu Kang Chun Liu Wei Liu Daihong Li Source Type: research
Editorial introductions
Curr Opin Organ Transplant. 2022 Aug 1;27(4):v-vi. doi: 10.1097/MOT.0000000000001000.NO ABSTRACTPMID:37718277 | DOI:10.1097/MOT.0000000000001000
Source: Current Opinion in Organ Transplantation - September 17, 2023 Category: Transplant Surgery Source Type: research
