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Long-term efficacy and safety profile of splenectomy for pediatric chronic immune thrombocytopenia
Int J Hematol. 2023 Jan 9. doi: 10.1007/s12185-022-03529-z. Online ahead of print.ABSTRACTThere are few reports of the long-term efficacy of splenectomy in children with immune thrombocytopenia (ITP). In a 33-year period, we performed splenectomies in 23 pediatric patients with ITP at a single institution in Japan. The age at surgery was 5-22 years with a median of 10 years. The follow-up period was 1-141 months with a median of 48 months. Before surgery, we confirmed the presence or absence of the accessory spleen by contrast-enhanced CT scan and we recommended vaccination with pneumococcal vaccine. Four patients underwen...
Source: International Journal of Hematology - January 9, 2023 Category: Hematology Authors: Kyohei Isshiki Makiko Mori Tomoya Irikura Takahiro Ishikawa Mamoru Honda Ryota Kaneko Yuichi Mitani Hirohito Kubota Kohei Fukuoka Koichi Oshima Yuki Arakawa Katsuyoshi Koh Source Type: research

Community-Acquired Pneumonia in Adults: Rapid Evidence Review
Am Fam Physician. 2022 Jun 1;105(6):625-630.ABSTRACTCommunity-acquired pneumonia (CAP) is a common condition with a hospitalization rate of about 2% in people 65 years or older and is associated with a 30-day mortality rate of 6% in hospitalized patients. In studies conducted before the COVID-19 pandemic, a bacterial pathogen was identified in 11% of patients, a viral pathogen in 23% of patients, and no organism in 62% of patients. Certain signs and symptoms can be helpful in diagnosing CAP and selecting imaging studies. Diagnosis is usually made with a combination of history, physical examination, and findings on chest ra...
Source: American Family Physician - June 15, 2022 Category: Primary Care Authors: Jason Womack Jill Kropa Source Type: research

A case of fulminant pneumococcus meningoencephalitis progressing with white matter involvement despite two doses of conjugated pneumococcus vaccine
CONCLUSION: Such diffuse white matter lesions among pediatric patients with Streptococcus pneumonia meningoencephalitis despite two doses of PCV have not been reported previously.PMID:33372445 | DOI:10.24953/turkjped.2020.06.018
Source: The Turkish Journal of Pediatrics - December 29, 2020 Category: Pediatrics Authors: Ebru Azapa ğası Tan ıl Kendirli G ökçen Öz Tuncer Serhan Özcan Halil Özdemir Suat Fit öz Erdal İnce Source Type: research