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Total 41502 results found since Jan 2013.

FOXO1 regulates NLRP3 inflammasome proteins in LPS-induced cardiotoxicity
CONCLUSION: FOXO1 overexpression attenuated apoptosis, ROS generation, and inflammation, whereas FOXO1 inhibition aggravated LPS-induced cardiomyocyte injury via the NLRP3 inflammasome signaling pathway.PMID:37692952 | PMC:PMC10492091
Source: American Journal of Translational Research - September 11, 2023 Category: Research Authors: Hui Zhao Lingcun Qin Ruyi Wang Dejie Qu Suting Li Source Type: research

Detection of Opportunistic Fungi from the Bronchoalveolar Lavage Specimens of Patients with Pulmonary Diseases
CONCLUSIONS: Due to the presence of a large number of fungi in the BAL samples and possible physical interference with the selected drugs for treatment, we draw the attention of pulmonologists to this important issue. Rapid diagnosis of fungal infections is essential to optimize treatments and outcomes.PMID:37694245 | PMC:PMC10492593 | DOI:10.4103/abr.abr_297_22
Source: Biomed Res - September 11, 2023 Category: Research Authors: Sahar Kianipour Parvin Dehghan Mohammad Emami Ardestani Source Type: research

Effects of Dichloromethane and N-Butanol Fractions of < em > Nigella sativa < /em > on ACHN and GP-293 Cell Line Morphology, Viability, and Apoptosis
CONCLUSION: Our findings demonstrated that these two fractions of N. sativa induce inhibitory effects on the ACHN cell line morphology and viability. These effects were lower than those induced by the total extract. In addition, the two fractions caused more marked effects in the renal cancer cell line compared with the GP-293 cell line.PMID:37694244 | PMC:PMC10492620 | DOI:10.4103/abr.abr_394_22
Source: Biomed Res - September 11, 2023 Category: Research Authors: Samira Shahraki Sara Hosseinian Elham Shahraki Mehdi Kheirandish Abolfazl Khajavirad Source Type: research

Perioperative Anxiolysis and Analgesic Effect after Premedication with Melatonin and Pregabalin in Total Hip Arthroplasty under Spinal Anaesthesia: A Prospective Comparative Trial
CONCLUSIONS: Pregabalin was found better for perioperative anxiolysis, post-operative analgesia and for prolongation of duration of spinal anaesthesia when compared to melatonin.PMID:37694243 | PMC:PMC10492595 | DOI:10.4103/abr.abr_323_22
Source: Biomed Res - September 11, 2023 Category: Research Authors: Akash Mishra Vinod Kumar Srivastava Ravi Prakash Neel Kamal Mishra Jyotsna Agarwal Shruti Kabi Source Type: research

Evaluation of the Effect of Aripiprazole Supplementation in the Prevention of Delirium in Patients Admitted to the General Intensive Care Unit
CONCLUSION: The use of aripiprazole with the approach of reducing the risk or controlling the occurrence of delirium on patients admitted to the intensive care unit, despite creating some beneficial effects such as reducing the length of hospital stay in the ICU, cannot be clearly and significantly effective.PMID:37694242 | PMC:PMC10492625 | DOI:10.4103/abr.abr_314_21
Source: Biomed Res - September 11, 2023 Category: Research Authors: Mehranoosh Nouri Sohrab Salimi Mohsen Kosha Dariush Abtahi Source Type: research

Status of Hypertension Control in Urban Slums of Central India: A community Health Worker-Based Two-Year Follow-Up
CONCLUSION: We found about six of every ten individuals with HTN were on treatment, and about four were optimally controlled. These findings provide a benchmark for NPCDCS, in terms of achievable goals within short periods of follow-up.PMID:37694241 | PMC:PMC10492608 | DOI:10.4103/abr.abr_266_22
Source: Biomed Res - September 11, 2023 Category: Research Authors: Abhijit Pakhare Anuja Lahiri Neelesh Shrivastava Krishna N Subba Vaishnavi Veera Durga Kurra Ankur Joshi Shubham Atal Sagar Khadanga Rajnish Joshi Source Type: research

A Comparative Study of Dialectical Behavior Therapy and Aripiprazole on Marital Instability of in Patients with Hypersexual
CONCLUSION: DBT and the drug aripiprazole cannot have a significant effect on the marital instability in patients.PMID:37694240 | PMC:PMC10492616 | DOI:10.4103/abr.abr_161_22
Source: Biomed Res - September 11, 2023 Category: Research Authors: Zahra Tavakoli Hasan Rezaei-Jamalouei Hamid Kazemi-Zahrani Mohammad Hatef Khorrami Iman Ghanaat Source Type: research

Effect of Oral Prednisolone on Pain after Tonsillectomy with Sutures: A Randomized Clinical Trial
CONCLUSION: Numerous studies have been conducted on the effect of intravenous corticosteroids on this pain. However, there is no consensus on the analgesic role of oral corticosteroids for post-tonsillectomy pain. The present study showed that oral prednisolone is effective on post-operative pain compared to a placebo.PMID:37694239 | PMC:PMC10492605 | DOI:10.4103/abr.abr_410_22
Source: Biomed Res - September 11, 2023 Category: Research Authors: Amin Shayan Nezammedin Berjis Sayed Mostafa Hashemi Source Type: research

The Effect of Lower Limb Position on Anterior Cruciate Ligament Reconstruction on Uncommon Complications after Surgery
CONCLUSIONS: There is no difference between compartment syndrome and deep vein thrombosis in different situations, therefore, the surgeon should operate in any position he is skilled in. Also, surgeons should always pay special attention to these complications and provide necessary training to patients in order to prevent them.PMID:37694238 | PMC:PMC10492626 | DOI:10.4103/abr.abr_34_22
Source: Biomed Res - September 11, 2023 Category: Research Authors: Hamidreza Aslani Sona Bonakdar Farzad Amoozade Mona Gorji Amir H Gholami Katayoun Tajic Morteza Gholipour Source Type: research

A Study on Glycopeptide-Resistant Genotypes among Clinical Isolates of < em > Enterococcus < /em > with Van B Phenotype
CONCLUSION: Heterogeneous resistance among clinical isolates of Enterococcus faecalis was observed in our study. The predominant phenotype and genotype detected among clinical isolates were Van A.PMID:37694237 | PMC:PMC10492609 | DOI:10.4103/abr.abr_133_21
Source: Biomed Res - September 11, 2023 Category: Research Authors: Reena Rajan Source Type: research

Motor Dysfunction of Gastric Antral Smooth Muscle in Diabetic Rats: Contribution of ATP-Dependent Potassium Channels
CONCLUSION: These results propose that KATP channels may contribute to the development of gastric motility disorders in diabetes.PMID:37694236 | PMC:PMC10492619 | DOI:10.4103/abr.abr_44_23
Source: Biomed Res - September 11, 2023 Category: Research Authors: Fatameh Khoshavi Najafabadi Hassan Sadraei Nasrin Mehranfard Maedeh Ghasemi Source Type: research

The Association of Demographic Characteristics with the Rate of Weight Loss and Changes in Nutritional Factors (Albumin, Vitamin D3, Ferritin) One Year after One Anastomosis Gastric Bypass
CONCLUSION: Some demographic characteristics such as age, gender, and marital status seem to affect the rate of weight loss or ferritin level one year after OAGB.PMID:37694235 | PMC:PMC10492623 | DOI:10.4103/abr.abr_442_22
Source: Biomed Res - September 11, 2023 Category: Research Authors: Masoud Sayadishahraki Atefe Salehi Source Type: research

Detection of Genes Related to Linezolid Resistance ( < em > poxtA < /em > , < em > cfr < /em > , and < em > optrA < /em > ) in Clinical Isolates of < em > Enterococcus spp < /em > . from Humans: A First Report from Iran
CONCLUSION: This is the first study to report the detection of linezolid resistance genes (cfr, optrA, and poxtA) in clinical Enterococcus spp. isolates from Iran, conducted at Isfahan University of Medical Sciences hospitals. The emergence of enterococcal strains that resist linezolid is concerning as it can lead to the spread of resistant strains among patients, resulting in treatment failure.PMID:37694234 | PMC:PMC10492618 | DOI:10.4103/abr.abr_74_23
Source: Biomed Res - September 11, 2023 Category: Research Authors: Majid Torabi Jamshid Faghri Farkhondeh Poursina Source Type: research

Comparison of Blood Lead Levels in Children and Adolescents with and without Functional Abdominal Pain
CONCLUSION: We found that the lead level was higher in patients with FGID than in the controls; however, this difference was not significantly different. This might be because of elevated lead levels in both groups. Future ecological studies with a large sample size are necessary in this regard.PMID:37694233 | PMC:PMC10492617 | DOI:10.4103/abr.abr_250_22
Source: Biomed Res - September 11, 2023 Category: Research Authors: Fatemeh Famouri Maryam Yazdi Awat Feizii Hossein Saneian Peiman Nasri Roya Kelishadi Source Type: research

Study of Auditory Brainstem Evoked Response at Varying Frequencies in Subclinical Hypothyroid Subjects
CONCLUSION: BERA study at 6 KHz and 80 dB detects central neuropathy earlier in subclinical hypothyroid patients.PMID:37694232 | PMC:PMC10492596 | DOI:10.4103/abr.abr_418_22
Source: Biomed Res - September 11, 2023 Category: Research Authors: Indira Jha Kabir Alam Kaushal K Keshari Niska Sinha Tarun Kumar Source Type: research