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Abstracts of Presentations at the Association of Clinical Scientists 143 < sup > rd < /sup > Meeting Louisville, KY May 11-14,2022
Conclusion: These assays are suitable for routine diagnostic. The UltraFast NextGenPCR is the fastest with average time (30mins), followed by Agilent (2 hrs) and MassArray (6hrs). Upon completion of this activity, participants should be able to examine, measure and compare results from different assays for SARS detection, evaluate and diagnose accurately, as well as being able to plan, organize and recommend a diagnostic procedure for diagnostic laboratory. Key words: SARS-CoV-2, RNA extraction, RT-PCR, limit of detection, quantification cycle, COVID-19, in vitro diagnostic tests, Agilent, Massarray, Ultrafast. [20] From t...
Source: Annals of Clinical and Laboratory Science - July 1, 2022 Category: Laboratory Medicine Source Type: research

Decline in pneumococcal nasopharyngeal carriage in children 6-23  months with respiratory illnesses following pneumococcal conjugate vaccine implementation
CONCLUSIONS: Following 7-valent PCV/ PCV13 introduction, pneumococcal carriage rates declined in respiratory diseases, but not in healthy children and children without respiratory infections. These trends suggest that a reduction in pneumococcal carriage rates during respiratory infections indicates a decline in respiratory infections caused by VT, while carriage rates in non-respiratory cases reflect non-VT predominance, that have low disease potential for respiratory disease.PMID:34481698 | DOI:10.1016/j.vaccine.2021.08.082
Source: Vaccine - September 5, 2021 Category: Allergy & Immunology Authors: Leore Kotler David Greenberg Noga Givon-Lavi Bart Adriaan van der Beek Ron Dagan Shalom Ben-Shimol Source Type: research

Community-Acquired Pneumonia
Ann Intern Med. 2022 Apr 12. doi: 10.7326/AITC202204190. Online ahead of print.ABSTRACTCommunity-acquired pneumonia is an important cause of morbidity and mortality. It can be caused by bacteria, viruses, or fungi and can be prevented through vaccination with pneumococcal, influenza, and COVID-19 vaccines. Diagnosis requires suggestive history and physical findings in conjunction with radiographic evidence of infiltrates. Laboratory testing can help guide therapy. Important issues in treatment include choosing the proper venue, timely initiation of the appropriate antibiotic or antiviral, appropriate respiratory support, d...
Source: Annals of Internal Medicine - April 11, 2022 Category: Internal Medicine Authors: Michael B Rothberg Source Type: research

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