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Total 66131 results found since Jan 2013.
Cone-beam computed tomographic evaluation of dimensional hard tissue changes following alveolar ridge preservation techniques of different bone substitutes: a systematic review and meta-analysis
CONCLUSIONS: Less vertical and horizontal bone reduction was observed when xenogenic graft materials were used than when allogenic graft materials were used; however, the loss of alveolar ridge dimensions could not be completely prevented by any graft material.PMID:35187870 | PMC:PMC8860760 | DOI:10.5051/jpis.2007100355
Source: Journal of Periodontal and Implant Science - February 21, 2022 Category: Dentistry Authors: Finn Niclas Pickert Simon Spalthoff Nils-Claudius Gellrich Juan Antonio Blaya T árraga Source Type: research
Impact of low-dose computed tomography (LDCT) screening on lung cancer-related mortality
CONCLUSIONS: The current evidence supports a reduction in lung cancer-related mortality with the use of LDCT for lung cancer screening in high-risk populations (those over the age of 40 with a significant smoking exposure). However, there are limited data on harms and further trials are required to determine participant selection and optimal frequency and duration of screening, with potential for significant overdiagnosis of lung cancer. Trials are ongoing for lung cancer screening in non-smokers.PMID:35921047 | DOI:10.1002/14651858.CD013829.pub2
Source: Cancer Control - August 3, 2022 Category: Cancer & Oncology Authors: Asha Bonney Reem Malouf Corynne Marchal David Manners Kwun M Fong Henry M Marshall Louis B Irving Ren ée Manser Source Type: research
Contrast-enhanced ultrasound for the diagnosis of hepatocellular carcinoma in adults with chronic liver disease
CONCLUSIONS: We found that by using CEUS, as an add-on test following abdominal ultrasound, to diagnose hepatocellular carcinoma of any size and stage, 22% of people with hepatocellular carcinoma would be missed, and 6% of people without hepatocellular carcinoma would unnecessarily undergo further testing or inappropriate treatment. As to resectable hepatocellular carcinoma, we found that 23% of people with resectable hepatocellular carcinoma would incorrectly be unresected, while 8% of people without hepatocellular carcinoma would undergo further inappropriate testing or treatment. The uncertainty resulting from the high ...
Source: Cochrane Database of Systematic Reviews - September 2, 2022 Category: General Medicine Authors: Mirella Fraquelli Tin Nadarevic Agostino Colli Cristina Manzotti Vanja Giljaca Damir Miletic Davor Štimac Giovanni Casazza Source Type: research
Ataluren and similar compounds (specific therapies for premature termination codon class I mutations) for cystic fibrosis
CONCLUSIONS: There is currently insufficient evidence to determine the effect of ataluren as a therapy for people with CF with class I mutations. One trial reported favourable results for ataluren in a post hoc subgroup analysis of participants not receiving chronic inhaled aminoglycosides, but these were not reproduced in the later trial, suggesting that the earlier results may have occurred by chance. Future trials should carefully assess for adverse events, notably renal impairment, and consider the possibility of drug interactions. Cross-over trials should be avoided, given the potential for the treatment to change the...
Source: Cochrane Database of Systematic Reviews - March 3, 2023 Category: General Medicine Authors: Aisha A Aslam Ian P Sinha Kevin W Southern Source Type: research
