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Vaccination: Malaria Vaccine

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Total 1513 results found since Jan 2013.

Transmission-Blocking Preventive Measures for Infectious Diseases: Altruism, Solidarity, and the Common Good
Am J Trop Med Hyg. 2021 Mar 11:tpmd201005. doi: 10.4269/ajtmh.20-1005. Online ahead of print.ABSTRACTAiming to prevent the spread of contagious diseases has long been a central tenet of public health. In the present time, divisive political responses to mask wearing to prevent SARS-CoV-2 transmission have competed with sound public health advice for public attention. Here, we draw parallels in terms of individualism versus societal solidarity between the slow and ponderous development of transmission-blocking vaccines for malaria and advocacy for mask wearing to prevent COVID-19.PMID:33705347 | DOI:10.4269/ajtmh.20-1005
Source: The American Journal of Tropical Medicine and Hygiene - March 11, 2021 Category: Tropical Medicine Authors: Laine Garber Joseph M Vinetz Source Type: research

Infectious diseases in returned travellers, NSW, 2010-2011
CONCLUSION: A large proportion of selected enteric and vectorborne disease case notifications were associated with overseas travel. All potential travellers should be made aware of the risks and available preventive measures, such as vaccination against hepatitis A and typhoid fever, taking precautions with food and water and use of malaria chemoprophylaxis, where appropriate. Improvements in data on risk factors, reason for travel and barriers to the use of preventive measures would better inform prevention strategies.PMID:24939227 | DOI:10.1071/NB13005
Source: New South Wales Public Health Bulletin - June 19, 2014 Category: Health Management Authors: Praveena Gunaratnam Sean Tobin Holly Seale Jeremy M McAnulty Source Type: research

Inclusion of an Optimized < em > Plasmodium falciparum < /em > Merozoite Surface Protein 2-Based Antigen in a Trivalent, Multistage Malaria Vaccine
In this study, we exploited the benefits of rPfMSP8 as a carrier to optimize a rPfMSP2-based subunit vaccine. rPfMSP2 and chimeric rPfMSP2/8 vaccines produced in Escherichia coli were evaluated in comparative immunogenicity studies in inbred (CB6F1/J) and outbred (CD1) mice, varying the dose and adjuvant. Immunization of mice with both rPfMSP2-based vaccines elicited high-titer anti-PfMSP2 Abs that recognized the major allelic variants of PfMSP2. Vaccine-induced T cells recognized epitopes present in both PfMSP2 and the PfMSP8 carrier. Competition assays revealed differences in Ab specificities induced by the two rPfMSP2-b...
Source: Journal of Immunology - April 1, 2021 Category: Allergy & Immunology Authors: Jacqueline S Eacret Elizabeth M Parzych Donna M Gonzales James M Burns Source Type: research

Infectious diseases in returned travellers, NSW, 2010-2011
CONCLUSION: A large proportion of selected enteric and vectorborne disease case notifications were associated with overseas travel. All potential travellers should be made aware of the risks and available preventive measures, such as vaccination against hepatitis A and typhoid fever, taking precautions with food and water and use of malaria chemoprophylaxis, where appropriate. Improvements in data on risk factors, reason for travel and barriers to the use of preventive measures would better inform prevention strategies.PMID:24939227 | DOI:10.1071/NB13005
Source: New South Wales Public Health Bulletin - June 19, 2014 Category: Health Management Authors: Praveena Gunaratnam Sean Tobin Holly Seale Jeremy M McAnulty Source Type: research

Inclusion of an Optimized < em > Plasmodium falciparum < /em > Merozoite Surface Protein 2-Based Antigen in a Trivalent, Multistage Malaria Vaccine
In this study, we exploited the benefits of rPfMSP8 as a carrier to optimize a rPfMSP2-based subunit vaccine. rPfMSP2 and chimeric rPfMSP2/8 vaccines produced in Escherichia coli were evaluated in comparative immunogenicity studies in inbred (CB6F1/J) and outbred (CD1) mice, varying the dose and adjuvant. Immunization of mice with both rPfMSP2-based vaccines elicited high-titer anti-PfMSP2 Abs that recognized the major allelic variants of PfMSP2. Vaccine-induced T cells recognized epitopes present in both PfMSP2 and the PfMSP8 carrier. Competition assays revealed differences in Ab specificities induced by the two rPfMSP2-b...
Source: Journal of Immunology - April 1, 2021 Category: Allergy & Immunology Authors: Jacqueline S Eacret Elizabeth M Parzych Donna M Gonzales James M Burns Source Type: research