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Fight Aging! Newsletter, July 17th 2023
In conclusion, the longevity-associated genotype of FLT1 may confer increased lifespan by protecting against mortality risk posed by hypertension. We suggest that FLT1 expression in individuals with longevity genotype boosts vascular endothelial resilience mechanisms to counteract hypertension-related stress in vital organs and tissues. Resistance Exercise Slows the Onset of Pathology in a Mouse Model of Alzheimer's Disease https://www.fightaging.org/archives/2023/07/resistance-exercise-slows-the-onset-of-pathology-in-a-mouse-model-of-alzheimers-disease/ With the caveat that mouse models of Alzheimer's...
Source: Fight Aging! - July 16, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Sodium taurocholate hydrate inhibits influenza virus replication and suppresses influenza a Virus-triggered inflammation in vitro and in vivo
Int Immunopharmacol. 2023 Jun 29;122:110544. doi: 10.1016/j.intimp.2023.110544. Online ahead of print.ABSTRACTInfluenza A virus is an important respiratory pathogen that poses serious threats to human health. Owing to the high mutation rate of viral genes, weaker cross-protection of vaccines, and rapid emergence of drug resistance, there is an urgent need to develop new antiviral drugs against influenza viruses. Taurocholic acid is a primary bile acid that promotes digestion, absorption, and excretion of dietary lipids. Here, we demonstrate that sodium taurocholate hydrate (STH) exhibits broad-spectrum antiviral activity a...
Source: International Immunopharmacology - July 1, 2023 Category: Allergy & Immunology Authors: Xiaolu Sun Xiaotong Hu Qiang Zhang Li Zhao Xiaomei Sun Li Yang Meilin Jin Source Type: research

Top studies of 2022 relevant to primary care: From the PEER team
CONCLUSION: Research published in 2022 yielded several high-quality articles on various conditions relevant to primary care, including hypertension, heart failure, asthma, and diabetes.PMID:37172982 | PMC:PMC10177638 | DOI:10.46747/cfp.6905325
Source: Canadian Family Physician Medecin de Famille Canadien - May 12, 2023 Category: Primary Care Authors: Danielle Perry Samantha S Moe Betsy Thomas Adrienne J Lindblad Jessica Kirkwood Jamie Falk Jen Potter Allison Paige G Michael Allan Source Type: research

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