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Pneumococcal pep27-mutant inhibits Wnt5a expression via the regulation of T helper cells to attenuate colitis
Int Immunopharmacol. 2022 Jun 9;109:108927. doi: 10.1016/j.intimp.2022.108927. Online ahead of print.ABSTRACTInflammatory bowel disease (IBD) is a chronic gut inflammatory disease characterized by extensive colitis and remission of the symptoms. The incidence rate and prevalence of IBD are increasing worldwide; IBD affects millions of people, has poorly defined etiology, and often results in a failure of pharmacological interventions. Regardless of the cause, mucosal healing is indispensable for the regeneration of inflamed mucosa to ensure intestinal homeostasis. Intranasal immunization with the pneumococcal pep27 mutant ...
Source: International Immunopharmacology - June 12, 2022 Category: Allergy & Immunology Authors: Hamid Iqbal Gyu-Lee Kim Ji-Hoon Kim Prachetash Ghosh Masaud Shah Wonsik Lee Dong-Kwon Rhee Source Type: research

Human Adenovirus Serotype 3 Infection Modulates the Biogenesis and Composition of Lung Cell-Derived Extracellular Vesicles
This study might suggest EVs could be diagnostic and therapeutic advancement to Ad infections and other related viral infections. However, further investigation is warranted to explore the underlying mechanism(s).PMID:34926703 | PMC:PMC8677401 | DOI:10.1155/2021/2958394
Source: Cell Research - December 20, 2021 Category: Cytology Authors: Ayodeji O Ipinmoroti Brennetta J Crenshaw Rachana Pandit Sanjay Kumar Brian Sims Qiana L Matthews Source Type: research